Description
Topilepsin 100 (Topiramate) Coated Tablets 100 mg. №30
Ingredients
- Each coated tablet contains 100 mg of topiramate.
Dosage
- The usual starting dose is 25 mg once daily in the evening.
- The dose is then increased by 25-50 mg per week based on the patient’s response.
Indications
- Topilepsin 100 is indicated for the treatment of epilepsy in adults and children.
Contraindications
- Do not use Topilepsin 100 if you are allergic to topiramate or any other ingredients in the tablets.
Directions
- Swallow the tablets whole with a glass of water.
- Do not crush or chew the tablets.
Scientific Evidence
- Topiramate has been extensively studied for its efficacy in the treatment of epilepsy.
- Research published in the Journal of Neurology, Neurosurgery & Psychiatry demonstrated that topiramate is effective in reducing the frequency of seizures in patients with refractory epilepsy.
Additional Information
- It is important to follow the prescribed dosage and not to discontinue the medication abruptly.
- Topiramate exerts its antiepileptic effects by blocking voltage-dependent sodium channels, enhancing the activity of gamma-aminobutyric acid (GABA), and inhibiting glutamate receptors.
- These mechanisms help to stabilize electrical activity in the brain and reduce the likelihood of seizures.