Description

Transuloza (lactulose) paste for oral use 150 g. vial

Ingredients

Active ingredient: Lactulose
Other ingredients: Purified water, sorbitol, sodium benzoate, and citric acid.

Dosage

Adults: Take **10-20 grams** (15-30 mL) daily, divided into 2-3 doses.
Children: Dosage should be adjusted based on age and weight.

Indications

Transuloza paste is indicated for the treatment of constipation and hepatic encephalopathy.

Contraindications

Do not use Transuloza paste if you are allergic to any of the ingredients. Consult a healthcare provider before use if pregnant or breastfeeding.

Directions

Mix the prescribed dose with water or juice and drink immediately. Follow with additional water. Adjust dosage based on individual response.

Scientific Evidence

Lactulose, the active ingredient in Transuloza paste, works by increasing the water content and softening the stool, promoting bowel movements. It is also known to reduce blood ammonia levels in hepatic encephalopathy, improving cognitive function.

Additional Information

Transuloza paste may cause bloating and flatulence initially. These side effects usually subside with continued use. Ensure an an adequate fluid intake while using this medication.

Pharmacological Effects: Lactulose is a synthetic disaccharide that is not absorbed in the small intestine but is fermented by colonic bacteria, leading to an increase in osmotic pressure and acidification of the colonic contents. This results in the retention of water in the colon, softening the stool and promoting bowel movements.

Clinical Trials: Clinical studies have shown that lactulose is effective in the treatment of chronic constipation and hepatic encephalopathy. A study published in the Journal of Gastroenterology and Hepatology demonstrated that lactulose significantly reduced blood ammonia levels in patients with hepatic encephalopathy, leading to improved mental status and quality of life.