Transuloza (lactulose) paste for oral use 150 g. vial

Description

Transuloza (lactulose) paste for oral use 150 g. vial

Composition

active substances: 100 g of oral paste contains lactulose – 35 g, white soft paraffin – 21.45 g, mineral oil – 42.91 g;

Excipients: aspartame (E 951), cholesterol, lactic acid, bixin oil, mandarin oil, lemon oil, orange oil.

Dosage form

Oral paste.

Main physical and chemical properties: shiny paste, from yellow to orange-yellow color, opaque and dense, fine-grained with a characteristic odor.

Pharmacotherapeutic group

Osmotic laxatives.
ATX code A06A D61.

Pharmacological properties

This drug belongs to the group of osmotic laxative drugs used in gastroenterology.
The main active ingredient is lactulose, which has the property of being broken down in the intestine by intestinal bacteria. As a result of these processes, it turns into low molecular weight organic acids.
The latter cause a decrease in acidity in the colon, increasing the volume of its contents and exerting an osmotic effect. Due to the normalization of the consistency of feces, the motility of the large intestine is stimulated, constipation is corrected, the physiological digestive rhythm and the rhythm of bowel emptying are restored.
Lactulose also acts as a prebiotic, increasing the number of beneficial bacteria in the gut, specifically bifidobacteria and lactobacilli. It also inhibits the growth of bacteria that may be pathogenic, such as Clostridium or E. coli. Thus, the balance of intestinal microflora is normalized.

Indications

This drug Transuloza paste is used to treat constipation of various etiologies.
In particular, it is used for:

• regulation of the physiological rhythm of the intestine with constipation;
• treatment of conditions requiring relief of bowel movements (hemorrhoids, conditions after operations on the large intestine and anorectal zone;
• treatment of portosystemic hepatic encephalopathy – treatment and prevention of hepatic coma and precoma.

Contraindications

Do not apply if the patient has hypersensitivity (allergy).
Also, use is contraindicated for:

• galactosemia, phenylketonuria;
• intestinal obstruction;
• perforation of the digestive tract;
• the risk of perforation of the digestive tract.

It is not used in pediatrics.

Application during pregnancy and lactation

This drug can be used during pregnancy and during breastfeeding, since the systemic effect of lactulose on a pregnant woman is insignificant. Also, no consequences for the fetus are expected.

Method of administration and dosage

Transuloza paste is usually taken in the evening with a little water.
The dose and regimen of the drug should be adjusted in accordance with the needs of the patient.
During therapy with laxatives, it is recommended to consume a sufficient amount of liquid (1.5-2 liters per day, which corresponds to 8-10 glasses).
The recommended daily dosage is 1-3 scoops, once a day.
You should not take the drug while lying down or just before going to bed.
The duration of the course of treatment is no more than 8 days.
Elderly patients, as well as patients suffering from renal or hepatic insufficiency, do not need dosage adjustment.

Overdose

When taking excessive dosages, the patient may experience:

• abdominal pain;
• diarrhea.

It is recommended to stop taking the drug or reduce the dosage, correct electrolyte imbalance in case of excessive fluid loss, which may be caused by diarrhea or vomiting.

Side effects

Therapy with this drug can cause adverse reactions, especially at the beginning of treatment. Among them were observed:

• flatulence;
• abdominal pain, diarrhea (if the recommended dosage is exceeded);
• possible discomfort, itching in the anus;
• slight decrease in body weight.

When using large therapeutic dosages, used for a long time, electrolyte imbalance may occur (due to prolonged significant dilution of the stool, diarrhea). Most often, this effect is observed in patients with hepatic insufficiency and encephalopathy, which should be taken into account in the treatment process.
In case of any unusual side effects, you should consult your doctor to adjust the course of treatment.