Trigan-D (paracetamol, dicyclomine) 500/20 mg. tablets №10

Description

Ingredients:

active substances: paracetamol, dicyclomine hydrochloride;

1 tablet contains paracetamol 500 mg, dicyclomine hydrochloride 20 mg;

excipients: sodium starch glycolate, polyvinylpyrrolidone, microcrystalline cellulose, silicon dioxide, colloidal anhydrous corn starch, magnesium stearate.

Medicinal form. Tablets.

White or off-white round tablets scored on one side with beveled edges and flat surface.

Pharmacotherapeutic group. Analgesics and antipyretics. Paracetamol combination without psycholeptics. ATX code N02B E51.

A combined drug that has analgesic and antispasmodic effects.

Paracetamol has an analgesic, antipyretic and minor anti-inflammatory effect. The mechanism of action is inhibition of cyclooxygenase-1 and, to a lesser extent, cyclooxygenase-2 in peripheral tissues and the central nervous system, as a result of which inhibition of the biosynthesis of prostaglandins – modulators of pain sensitivity and thermoregulation of inflammation.

Dicyclomine hydrochloride d is a tertiary amine. It has anticholinergic activity and reduces the tone of smooth muscles, eliminates pain, blocks antagonistic activity. Dicyclomine hydrochloride selectively paralyzes M-cholinereactive structures by blocking the transmission of impulses of postganglionic cholinergic nerves to the effector organs innervated by them. Causes relaxation of smooth muscles, showing an antispasmodic effect in spasms of smooth muscles of the stomach, intestines, biliary tract, urogenital and vascular systems.

Indications.

Pain syndromes with a spastic component of various origins:

• headache;
• toothache;
• muscle pain, neuralgia;
• rheumatic pain of sciatica;
• renal colic;
• menstrual pain.

Contraindications.

Increased sensitivity to the components of Trigan-D (paracetamol, dicyclomine). Glaucoma tachycardia urinary tract obstruction benign prostatic hypertrophy with a tendency to delay urination myasthenia severe kidney and/or liver dysfunction glucose-6-phosphate dehydrogenase deficiency alcoholism blood diseases pronounced anemia leukopenia; dynamic intestinal obstruction, obstructive diseases of the gastrointestinal tract, urinary and biliary tract with impaired patency, peptic ulcer of the stomach or duodenum, reflux esophagitis; acute bleeding; congenital hyperbilirubinemia (Gilbert Dubin-Johnson and Rotor syndromes).

Dosage and Administration.

Trigan-D (paracetamol, dicyclomine) is taken orally with a small amount of liquid (200 ml).

Adults and children over 15 years of age: 1-2 tablets, depending on the severity of pain, from 1 to 4 times a day. When carrying out therapy for adults, it is advisable to start with four tablets per day. The maximum dose can be increased to 8 tablets per day, provided that it is well tolerated and there are no side effects

Children: 7 to 13 years: 1/2 tablet 1-2 times a day;

13 to 15 years: 1 tablet 1-3 times a day.

The duration of treatment is determined by the doctor individually, depending on the patient’s condition and reaction.