Description

Zavedos (idarubicin hydrochloride) lyophilisate for infusions 5 mg. vial №1

Ingredients

Active ingredient: idarubicin hydrochloride. Inactive ingredients may include lactose, hydrochloric acid, and sodium hydroxide.

Dosage

Dosage: The dosage of Zavedos is individualized based on the patient’s condition, weight, and overall health. It is administered intravenously by a healthcare professional.

Indications

Indications: Zavedos is indicated for the treatment of acute myeloid leukemia (AML) in adults. It works by stopping the growth of cancer cells.

Contraindications

Contraindications: Do not use Zavedos if you are allergic to idarubicin or any of the inactive ingredients. It is not recommended for use during pregnancy.

Directions

Administration: Zavedos is administered as an intravenous infusion over a specific period as directed by a healthcare provider. It is crucial to follow the recommended dosage and infusion rate.

Scientific Evidence

Pharmacological Effects: Idarubicin hydrochloride, the active ingredient in Zavedos, belongs to a class of medications known as anthracyclines. It works by interfering with the growth and spread of cancer cells in the body. Studies have shown that idarubicin is effective in inducing remission in patients with AML.

Clinical Trials: Clinical trials have demonstrated the efficacy of Zavedos in the treatment of AML. A study published in the Journal of Clinical Oncology showed that idarubicin-based regimens resulted in higher response rates and improved overall survival compared to other chemotherapy agents.

Additional Information

Zavedos should only be administered under the supervision of a qualified healthcare provider experienced in the use of cytotoxic chemotherapy agents. It is essential to monitor blood counts regularly during treatment to assess the response and manage potential side effects.

Prior to starting Zavedos treatment, inform your healthcare provider about any existing medical conditions, ongoing medications, and allergies. Adhere strictly to the prescribed dosage and schedule to maximize the benefits of the medication.