Description

Zinacef (cefuroxime) powder for solution for injections 1500 mg. №1 vial

Ingredients

Active ingredient: cefuroxime. Inactive ingredients may include sodium carbonate, arginine, and dextran.

Dosage

Dosage: The usual adult dose is 750 mg to 1.5 grams every 8 hours, depending on the severity of the infection.

Indications

Indications: Zinacef is indicated for the treatment of infections caused by susceptible strains of bacteria.

Contraindications

Contraindications: Do not use Zinacef if you are allergic to cefuroxime or any other cephalosporin antibiotics.

Directions

Administration: Zinacef is for intravenous or intramuscular use. Follow the instructions provided by your healthcare provider.

Scientific Evidence

Zinacef (cefuroxime) has been extensively studied for its efficacy in treating various bacterial infections. Research published in the Journal of Antimicrobial Chemotherapy demonstrated the effectiveness of cefuroxime in treating respiratory tract infections and skin and soft tissue infections. Clinical trials have shown high success rates in eradicating bacteria and improving patient outcomes.

Additional Information

It is important to complete the full course of treatment with Zinacef as prescribed by your healthcare provider, even if you start to feel better before the treatment is finished. Failure to complete the full course of antibiotics may result in the infection not being fully treated and could lead to antibiotic resistance.

Pharmacological Effects

Cefuroxime, the active ingredient in Zinacef, works by interfering with the synthesis of the bacterial cell wall, leading to the death of the bacteria. It exhibits bactericidal activity against a wide range of gram-positive and gram-negative bacteria. By disrupting the bacterial cell wall, cefuroxime effectively stops the growth and spread of the infection within the body.

Clinical Trials and Comparative Effectiveness

In comparative studies, Zinacef has shown similar or superior effectiveness compared to other antibiotics in the cephalosporin class. Clinical trials have demonstrated the rapid onset of action and high efficacy of cefuroxime in treating various infections. Additionally, Zinacef is well-tolerated with a low incidence of adverse effects, making it a favorable choice for many healthcare providers.

Overall, Zinacef (cefuroxime) powder for solution for injections 1500 mg. №1 vial is a potent antibiotic with a proven track record of efficacy in treating bacterial infections. Its pharmacological action, supported by scientific evidence and clinical trials, makes it a reliable choice for healthcare providers in managing a range of infections.