Zinacef (cefuroxime) powder for solution for injections 750 mg. №1 vial

Description

Zinacef (cefuroxime) powder for solution for injections 750 mg. №1 vial

Composition

active substance: cefuroxime;

1 vial contains cefuroxime (as cefuroxime sodium) 750 mg or 1.5 g

Dosage form

Powder for solution for injection.

Basic physical and chemical properties: white or cream-colored powder.

Pharmacotherapeutic group

Antibacterial agents for systemic use. Cephalosporins of the second generation. ATX code J01D C02.

Pharmacological properties

Indications

Zinacef powder for solution is used in the treatment of infectious and inflammatory diseases caused by bacteria susceptible to cefuroxime. The drug is used in therapy:

• bronchitis, pneumonia, infected bronchiectasis, lung abscess, infectious diseases of the chest, arising after surgery;
• meningitis;
• sore throat, otitis media, sinusitis, pharyngitis;
• erysipelas, boils, infected wounds;
• cystitis, pyelonephritis, asymptomatic bacteriuria, gonorrhea;
• osteomyelitis, septic arthritis;
• septicemia;
• infectious lesions of the pelvic organs;
• peritonitis.

In addition, Zinacef powder for solution is used to prevent infectious complications during operations on the abdominal and pelvic organs, as well as the heart, esophagus, lungs, blood vessels, bones and joints.

Contraindications

Zinacef powder for solution is not prescribed to patients with established intolerance to penicillins and cephalosporins, as well as with a tendency to bleeding and various diseases of the gastrointestinal tract.

Method of application and dose

Zinacef is intended for parenteral administration. Adult patients receive the drug every 8 hours at 750 mg. In the treatment of severe infections, the drug is administered intravenously 1.5 g every 8 hours. If necessary, the drug can be administered every 4 hours. The highest daily dose of Zinacef is 6 g.

In the treatment of most infections, the dosage of Zinacef from 750 to 1.5 g twice a day is considered effective. The child’s daily dose can vary from 30 to 100 mg per 1 kg of body weight of the child, divided into 3 or 4 doses.

Overdose

In case of Zinacef powder for solution overdose, patients experience motor arousal, manifested by tremor and convulsions. If symptoms of overdose occur, hemodialysis or peritoneal dialysis is performed to reduce the concentration of cefuroxime in the body.

Side effects

Occasionally, patients taking Zinacef develop headaches, convulsions, dizziness, decreased visual acuity, nausea, diarrhea, epigastric pain, candidal vaginitis, and renal impairment, dizziness, decreased visual acuity, and hearing loss.