Description

Zolev (levofloxacin) solution for infusions 5 mg/ml. 100 ml. vial №1

Ingredients

Active ingredient: Levofloxacin. Inactive ingredients may include sodium chloride, sodium hydroxide, hydrochloric acid, and water for injection.

Dosage

Dosage: The usual dose of Zolev for adults is 250 mg to 750 mg administered orally or intravenously once daily. Dosage adjustments may be necessary based on the severity of the infection.

Indications

Indications: Zolev is indicated for the treatment of various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and urinary tract infections.

Contraindications

Contraindications: Zolev is contraindicated in patients with a history of hypersensitivity to levofloxacin or other quinolone antibiotics.

Directions

Directions: Zolev should be administered as directed by a healthcare provider. It can be given by intravenous infusion over a specified period of time.

Scientific Evidence

Scientific Evidence: Studies have shown the efficacy of levofloxacin in treating a wide range of bacterial infections. Research published in the Journal of Antimicrobial Chemotherapy demonstrated the effectiveness of levofloxacin in treating community-acquired pneumonia.

Additional Information

Pharmacological Effects: Levofloxacin works by inhibiting bacterial DNA gyrase, thereby preventing DNA replication and ultimately leading to bacterial cell death. It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria.

Clinical Trials: Clinical trials have shown that Zolev is well-tolerated and effective in the treatment of various infections. A study published in Clinical Infectious Diseases demonstrated the clinical efficacy of levofloxacin in complicated skin and soft tissue infections.

Overall, Zolev (levofloxacin) solution for infusions is a potent antibiotic with a well-established efficacy profile supported by scientific research and clinical trials. It is a valuable option for healthcare providers in the management of bacterial infections.