Description

Zolmigren (zolmitriptan) Coated Tablets 2.5 mg. №10

Ingredients

Active ingredient: Zolmitriptan 2.5 mg.
Other ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, triacetin.

Dosage

Recommended dosage: 2.5 mg at the onset of migraine headache. A second dose may be taken after 2 hours if needed. Maximum dose: 10 mg in 24 hours.

Indications

Zolmigren (zolmitriptan) coated tablets are indicated for the acute treatment of migraine attacks with or without aura in adults.

Contraindications

Do not use Zolmigren (zolmitriptan) coated tablets if you have uncontrolled hypertension, ischemic heart disease, history of stroke or transient ischemic attack, peripheral vascular disease, or hemiplegic or basilar migraine.

Directions

Take Zolmigren (zolmitriptan) coated tablets orally with water. Do not crush or chew the tablets. It is recommended to take the medication as soon as migraine symptoms appear.

Scientific Evidence

Zolmitriptan, the active ingredient in Zolmigren tablets, is a selective serotonin receptor agonist that acts on the 5-HT1B/1D receptors in the brain. Studies have shown that zolmitriptan is effective in relieving migraine symptoms, including pain, nausea, and sensitivity to light and sound. Clinical trials have demonstrated its efficacy in providing rapid and sustained relief from migraine attacks.

Additional Information

Zolmigren (zolmitriptan) coated tablets are well-tolerated, with the most common side effects being mild and transient. It is important to follow the recommended dosage and not exceed the maximum daily dose. If migraine symptoms persist or worsen after taking the medication, consult a healthcare provider for further evaluation.

Pharmacologically, zolmitriptan works by constricting blood vessels in the brain and inhibiting the release of inflammatory neuropeptides. This action helps to reduce the pain and other symptoms associated with migraines. Compared to other triptans, zolmitriptan has shown similar efficacy but may have a faster onset of action in some individuals.

Research studies have highlighted the importance of early intervention with zolmitriptan in the management of migraines to achieve optimal outcomes and improve patient quality of life. The efficacy and safety profile of Zolmigren (zolmitriptan) coated tablets make it a valuable option for individuals suffering from migraines.