Description

Zoxon 4 (doxazosin) tablets 4 mg. №30

Ingredients

Active ingredient: Doxazosin mesylate 4 mg.

Dosage

Recommended dosage: The usual starting dose is 1 mg once daily. The dose may be increased gradually as needed.

Indications

Indicated for: Treatment of hypertension and benign prostatic hyperplasia.

Contraindications

Do not use if: Allergic to doxazosin or similar medications, have a history of orthostatic hypotension, or are pregnant.

Directions

Administration: Take the tablet by mouth with or without food. Follow the instructions of your healthcare provider.

Scientific Evidence

Doxazosin, the active ingredient in Zoxon 4 tablets, is an alpha-1 adrenergic blocker that works by relaxing blood vessels and improving blood flow. Studies have shown its effectiveness in lowering blood pressure and improving symptoms of benign prostatic hyperplasia. Research published in the Journal of Hypertension demonstrated that doxazosin effectively reduces blood pressure in patients with hypertension.

Additional Information

It is important to monitor blood pressure regularly while taking Zoxon 4 tablets. Inform your doctor of any side effects or concerns. Avoid sudden position changes to prevent dizziness.

Pharmacological Effects

Doxazosin acts selectively on alpha-1 adrenergic receptors in the smooth muscle of blood vessels and the prostate, leading to vasodilation and relaxation of the prostate muscles. This dual action helps in reducing blood pressure and relieving urinary symptoms associated with benign prostatic hyperplasia.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of doxazosin in managing hypertension and benign prostatic hyperplasia. In comparative studies, doxazosin has shown similar effectiveness to other alpha-blockers in treating these conditions but with potentially fewer side effects. Research in the American Journal of Medicine supports the use of doxazosin as a first-line treatment for hypertension.

• Study: “Efficacy of doxazosin in the treatment of hypertension.” Journal of Hypertension.
• Research: “Comparative effectiveness of alpha-blockers in benign prostatic hyperplasia.” American Journal of Medicine.