Description
Amigren (Sumatriptan) Capsules 100 mg. N3
Composition
Active ingredient: Sumatriptan succinate 100 mg.
Mechanism of Action
Sumatriptan is a selective serotonin receptor agonist that works by narrowing blood vessels in the brain, which helps to relieve migraine headaches.
Pharmacological Properties
Sumatriptan exerts its therapeutic effects by binding to serotonin receptors, leading to vasoconstriction of cranial blood vessels and inhibition of pro-inflammatory neuropeptide release.
Indications for Use
Amigren (Sumatriptan) capsules are indicated for the acute treatment of migraine attacks with or without aura.
Contraindications
Do not use Amigren (Sumatriptan) capsules if:
- You have uncontrolled hypertension.
- You have a history of heart disease.
- You are allergic to sumatriptan.
Side Effects
Common side effects of Amigren (Sumatriptan) capsules may include dizziness, drowsiness, chest discomfort, and tingling sensations. In rare cases, serious cardiovascular events such as heart attack or stroke may occur.
Usage Instructions
Recommended dosage: The usual adult dose is 25 mg to 100 mg taken as soon as migraine symptoms appear. Do not exceed 200 mg in a 24-hour period.
Administration: Take one capsule by mouth with water as soon as migraine symptoms appear. If the headache returns, a second capsule may be taken after 2 hours.
Benefits Compared to Analogues
Compared to other migraine medications, Sumatriptan has shown rapid onset of action and effective relief of migraine symptoms with a lower risk of recurrence.
Suitable Patient Groups
Amigren (Sumatriptan) capsules are suitable for use in adult patients experiencing acute migraine attacks. Special caution should be exercised when administering to elderly individuals or patients with renal impairment.
Storage and Shelf Life
Store Amigren (Sumatriptan) capsules in a cool, dry place away from direct sunlight. Keep out of reach of children. Check the expiration date on the packaging and do not use beyond the stated shelf life.
Packaging Description
Each package of Amigren (Sumatriptan) capsules contains 3 blister packs with a total of 9 capsules. The packaging is designed to maintain the stability and integrity of the capsules.
Clinical Evidence and Proven Effectiveness
Studies have shown that Sumatriptan is effective in treating acute migraines and can provide significant relief within 2 hours of administration. Clinical trials have demonstrated the efficacy of Sumatriptan in relieving migraine pain and associated symptoms such as nausea and sensitivity to light and sound. Patients treated with Sumatriptan reported a reduction in the severity and duration of migraines compared to placebo.
Additional Information
Important: Amigren (Sumatriptan) capsules are not intended for the prevention of migraines and should only be used during a migraine attack. Consult your healthcare provider before using Amigren (Sumatriptan) capsules, especially if you have any underlying medical conditions or are taking other medications.
