Description
Arifam (Indapamide) Tablets with Modified Release 1.5 mg/10 mg. №30
Composition
Active ingredient: Indapamide.
Other ingredients: lactose monohydrate, hypromellose, magnesium stearate, and more.
Mechanism of Action
Indapamide, a thiazide-like diuretic, acts on the distal convoluted tubule of the kidney to promote diuresis and lower blood pressure. It increases the excretion of sodium and water by the kidneys, aiding in blood pressure reduction. Additionally, it exhibits vasodilatory effects, further contributing to lowering blood pressure.
Indications for Use
Arifam tablets are indicated for the treatment of hypertension (high blood pressure).
Contraindications
Avoid using Arifam tablets if you are allergic to indapamide or any other ingredients in the formulation. Consult your healthcare provider before use if you have severe renal impairment.
Side Effects
Common side effects of Arifam may include electrolyte imbalances, hypokalemia, dizziness, and gastrointestinal disturbances. Contact your healthcare provider if you experience any severe or persistent side effects.
Usage Instructions
Take 1 tablet of Arifam daily, preferably in the morning, with or without food. Swallow the tablet whole with a glass of water. Do not exceed the recommended dose. Follow the dosage instructions provided by your healthcare provider.
Benefits Compared to Analogues
Arifam has shown efficacy in managing hypertension and reducing the incidence of stroke and other cardiovascular complications, making it a valuable option in the treatment of high blood pressure compared to other antihypertensive medications.
Suitable Patient Groups
Arifam is suitable for adults with hypertension. Dosage adjustments may be required for elderly patients or those with specific health conditions. Consult a healthcare professional for personalized recommendations.
Storage and Shelf Life
Store Arifam tablets in a cool, dry place away from direct sunlight. Keep them out of reach of children. Check the expiration date on the packaging and do not use the tablets beyond that date.
Packaging Description
Each package of Arifam contains 30 tablets with modified release, each tablet containing 1.5 mg of indapamide and 10 mg of additional ingredients.
Clinical Evidence and Proven Effectiveness
Indapamide, the active ingredient in Arifam tablets, has been extensively studied for its efficacy in managing hypertension and reducing cardiovascular risks. Clinical trials have shown that indapamide-based therapy significantly lowers blood pressure and decreases the incidence of stroke and other cardiovascular events. A study published in the Journal of Hypertension highlighted the positive outcomes of indapamide treatment compared to a placebo in reducing the risk of stroke.