Description
Carvidex (Carvedilol) Coated Tablets 12.5 mg. №20
Composition
The active ingredient in Carvidex is carvedilol. Each tablet contains 12.5 mg of carvedilol.
Mechanism of Action
Carvedilol is a non-selective beta-blocker with alpha-blocking activity. It works by blocking beta receptors in the heart and blood vessels, leading to a reduction in heart rate, blood pressure, and workload on the heart.
Pharmacological Properties
Carvedilol has anti-hypertensive and anti-arrhythmic properties. It also exhibits antioxidant effects and improves cardiac function in heart failure patients.
Indications for Use
- Treatment of high blood pressure
- Management of heart failure
- Post-myocardial infarction left ventricular dysfunction
Contraindications
Carvidex is contraindicated in:
- Patients with severe liver disease
- Individuals with asthma
- Patients with certain types of heart rhythm problems
- Those allergic to carvedilol or any ingredients in Carvidex
Side Effects
Common side effects of Carvidex may include dizziness, fatigue, low blood pressure, and bradycardia. Rare but serious side effects may include worsening heart failure and bronchospasm in patients with asthma.
Usage Instructions
Carvidex should be taken orally with food to enhance absorption and minimize gastrointestinal side effects. The usual starting dose is 12.5 mg once daily for the first two days, followed by an increase to 25 mg once daily. Dosage adjustments may be made by a healthcare provider based on individual response.
Benefits Compared to Analogues
Carvedilol offers the combined benefits of beta-blockade and alpha-blocking activity, making it effective in managing both hypertension and heart failure. Its antioxidant properties provide additional cardiovascular protection compared to some other beta-blockers.
Suitable Patient Groups
Carvidex is suitable for adult patients with hypertension, heart failure, or post-myocardial infarction left ventricular dysfunction. Dosage adjustments may be necessary for elderly patients or those with hepatic impairment.
Storage and Shelf Life
Store Carvidex in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use the product after the specified date.
Packaging Description
Carvidex is available in blister packs containing 20 coated tablets of 12.5 mg strength each. The packaging is designed to ensure the stability and integrity of the tablets until use.
