Description
Casarc (Candesartan Cilexetil) Tablets 16 mg. №30
Composition
The active ingredient in each tablet of Casarc is 16 mg of candesartan cilexetil.
Mechanism of Action
Casarc, containing candesartan cilexetil, is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal glands. By blocking the effects of angiotensin II, Casarc dilates blood vessels and reduces aldosterone secretion, leading to decreased blood pressure and improved cardiac function.
Pharmacological Properties
Casarc exerts its antihypertensive and heart failure management effects by inhibiting the renin-angiotensin-aldosterone system, resulting in vasodilation, reduced vascular resistance, and decreased sodium and water retention.
Indications for Use
Casarc is indicated for the treatment of hypertension and heart failure in adult patients to improve cardiovascular outcomes.
Contraindications
- Patients with a known hypersensitivity to candesartan cilexetil should not take Casarc.
- Casarc is contraindicated in patients with severe renal impairment due to the risk of further deterioration in renal function.
Side Effects
The use of Casarc may lead to common side effects such as dizziness, hypotension, hyperkalemia, and renal impairment. Patients should report any adverse reactions to their healthcare provider.
Usage Instructions
For adults, the typical dosage of Casarc is one tablet daily, administered orally with or without food. Dosage adjustments may be necessary based on individual patient response and tolerability. It is crucial to adhere to the prescribed dosage and follow the guidance of a healthcare professional.
Benefits Compared to Analogues
Casarc, with candesartan cilexetil as its active ingredient, offers advantages over other antihypertensive medications by providing effective blood pressure control, reducing the risk of cardiovascular events, and improving heart failure symptoms. Its once-daily dosing regimen enhances patient compliance and convenience.
Suitable Patient Groups
Casarc is suitable for adult patients with hypertension and heart failure who require ARB therapy. It is important to consider individual patient characteristics, such as age and comorbidities, when determining the suitability of Casarc for use in specific patient populations.
Storage and Shelf Life
Casarc should be stored at room temperature away from moisture and heat. The product should be kept in its original packaging to protect it from light. The shelf life of Casarc is typically indicated on the packaging and should be checked before use.
Packaging Description
Casarc is available in a package containing 30 tablets, with each tablet containing 16 mg of candesartan cilexetil. The packaging should include essential information such as dosage instructions, contraindications, and storage recommendations.
