Description
Ketorolak Ampoules 3% 1ml. №10
Composition
The active ingredient in Ketorolak Ampoules is Ketorolak. Each 1ml ampoule contains 3% Ketorolak.
Mechanism of Action
Ketorolak is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic, anti-inflammatory, and antipyretic properties. It works by inhibiting the enzyme cyclooxygenase, thereby reducing the synthesis of prostaglandins which are mediators of pain and inflammation.
Pharmacological Properties
Ketorolak exerts its pharmacological effects by blocking the production of prostaglandins, thereby providing pain relief and reducing inflammation. It is rapidly absorbed following administration and reaches peak plasma concentrations within 1-2 hours.
Indications for Use
Ketorolak Ampoules are indicated for the short-term management of moderate to severe acute pain that requires analgesia at the opioid level. They are commonly used in postoperative settings to provide effective pain relief.
Contraindications
- Patients with hypersensitivity to Ketorolak or any of the other ingredients should not use this medication.
- Individuals with active peptic ulcer disease or a history of recurrent peptic ulcer disease should avoid Ketorolak Ampoules.
- Patients with severe renal impairment or those at risk of renal failure due to volume depletion should not use Ketorolak.
Side Effects
Common side effects of Ketorolak Ampoules may include gastrointestinal discomfort, nausea, vomiting, dizziness, and headache. Serious side effects such as gastrointestinal bleeding, renal impairment, and allergic reactions may occur in rare cases.
Usage Instructions
Ketorolak Ampoules should be administered intramuscularly or intravenously as directed by a healthcare professional. The typical dosage is one ampoule every 4-6 hours. Do not mix Ketorolak with other solutions or medications.
Benefits Compared to Analogues
Ketorolak offers effective pain relief comparable to opioids but with a lower risk of addiction and respiratory depression. It provides rapid onset of action and can be administered parenterally for quick pain management.
Suitable Patient Groups
Ketorolak Ampoules can be used in various patient populations including adults, elderly patients, and adolescents for the management of acute pain. However, special caution is advised in pediatric patients and individuals with specific medical conditions.
Storage and Shelf Life
Ketorolak Ampoules should be stored at room temperature away from moisture and heat. Do not freeze. Check the expiration date on the packaging and do not use the product if expired.
Packaging Description
Ketorolak Ampoules are typically packaged in boxes containing multiple ampoules. Each ampoule is sealed to ensure sterility and should be inspected for any signs of damage or contamination before use.
