Description
Clobaza Cream 40 g
Ingredients
- Clobetasol propionate
- Propylene glycol
- White soft paraffin
- Cetostearyl alcohol
- Phosphoric acid
- Sodium hydroxide
Mechanism of Action
Clobetasol propionate exerts its effects by inhibiting the release of inflammatory mediators and suppressing the immune response in the skin. This leads to a reduction in redness, swelling, and itching.
Pharmacological Properties
Clobetasol propionate, the active ingredient in Clobaza Cream, demonstrates potent anti-inflammatory and anti-pruritic properties. It is a high-potency corticosteroid that effectively manages corticosteroid-responsive dermatoses.
Indications for Use
Clobaza Cream is indicated for the relief of inflammatory and pruritic manifestations associated with corticosteroid-responsive dermatoses, such as psoriasis, eczema, and dermatitis.
Contraindications
Do not use Clobaza Cream in patients with a history of hypersensitivity to any of its ingredients. It is important to perform a patch test before initiating treatment in individuals with sensitive skin.
Side Effects
Common side effects of Clobaza Cream may include skin atrophy, striae, telangiectasia, and perioral dermatitis. Prolonged use or excessive application can lead to systemic absorption and adverse effects such as Cushing’s syndrome.
Usage Instructions
Apply a thin layer of Clobaza Cream to the affected area once daily or as directed by a healthcare professional. Gently massage the cream into the skin until it disappears, and wash hands thoroughly after application.
Benefits Compared to Analogues
Clobaza Cream offers superior anti-inflammatory and anti-pruritic effects compared to other corticosteroid creams due to the high potency of clobetasol propionate. Its rapid onset of action and long duration of effect make it a preferred choice for managing severe dermatoses.
Suitable Patient Groups
Clobaza Cream is suitable for adult patients and adolescents over the age of 12 years. It should be used with caution in pediatric populations and avoided in infants unless prescribed by a healthcare provider.
Storage and Shelf Life
Store Clobaza Cream at room temperature away from moisture and heat. Keep the tube tightly closed when not in use. Check the expiration date on the packaging and do not use the cream beyond the stated shelf life.
Packaging Description
Clobaza Cream is available in a 40 g tube for topical application. The tube is designed for easy and precise dispensing of the cream, ensuring accurate dosage and minimal product wastage.
Clinical Evidence and Proven Effectiveness
Studies have shown the efficacy of clobetasol propionate in reducing inflammation and itching associated with various dermatological conditions. Research published in the Journal of Drugs in Dermatology highlighted the superior anti-inflammatory properties of clobetasol propionate compared to other corticosteroids.
Clinical trials have demonstrated the effectiveness of clobetasol propionate in the treatment of psoriasis, eczema, and dermatitis. A study in the Journal of the American Academy of Dermatology reported significant symptom improvement with the use of clobetasol propionate cream.
