Description
Clodifen (Diclofenac) Gel 50 mg/g, 45 g Tube
Ingredients
Active Ingredient: Diclofenac 50 mg/g.
Mechanism of Action
Clodifen gel works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. By reducing the levels of prostaglandins, diclofenac helps alleviate pain and swelling in the affected joints, providing relief to individuals suffering from arthritis.
Pharmacological Properties
Diclofenac, the active ingredient in Clodifen gel, belongs to the class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It exerts its anti-inflammatory and analgesic effects by inhibiting the enzyme cyclooxygenase, thereby reducing the synthesis of prostaglandins.
Indications for Use
Clodifen gel is indicated for the relief of pain and inflammation associated with osteoarthritis and rheumatoid arthritis.
Contraindications
Do not use Clodifen gel if you are allergic to diclofenac or have a history of allergic reactions to NSAIDs. Avoid use in patients with a known hypersensitivity to any component of the gel.
Side Effects
Common side effects of Clodifen gel may include skin irritation, itching, or rash at the application site. In rare cases, systemic side effects such as gastrointestinal disturbances or allergic reactions may occur. Discontinue use and consult a healthcare provider if you experience any adverse reactions.
Usage Instructions
Dosage: Apply a thin layer of Clodifen gel to the affected area 3-4 times daily. Do not exceed the recommended dose.
Directions: Clean and dry the affected area before applying the gel. Gently massage the gel into the skin until fully absorbed. Wash hands after application.
Benefits Compared to Analogues
Clodifen gel offers targeted relief of pain and inflammation with a lower risk of systemic side effects compared to oral NSAIDs. Its topical application allows for direct delivery to the affected joints, resulting in faster onset of action and potentially lower overall drug exposure.
Suitable Patient Groups
Clodifen gel is suitable for adult patients with osteoarthritis and rheumatoid arthritis. It may also be used in elderly individuals who may prefer topical treatments over oral medications. Consult a healthcare provider for appropriate use in children or adolescents.
Storage and Shelf Life
Store Clodifen gel at room temperature, away from moisture and heat. Keep the tube tightly closed when not in use. Check the expiration date on the packaging and do not use the product if it has expired.
Packaging Description
Clodifen gel is supplied in a 45 g tube for topical application. The tube is designed for easy and precise dispensing of the gel. The packaging includes detailed instructions for use and storage.
Clinical Evidence and Proven Effectiveness
Scientific studies have shown that diclofenac, the active ingredient in Clodifen gel, effectively reduces pain and inflammation in patients with osteoarthritis and rheumatoid arthritis. A study published in the Journal of Clinical Rheumatology demonstrated the superior efficacy of diclofenac gel compared to placebo in managing arthritis symptoms.
