Description

Co-Prenesa Tablets 4 mg/1.25 mg

Ingredients

Active ingredients: Perindopril tert-butylamine 4 mg and Indapamide 1.25 mg.

Mechanism of Action

Pharmacological Effects: Perindopril, an ACE inhibitor, inhibits the conversion of angiotensin I to angiotensin II, resulting in vasodilation and reduced aldosterone secretion. Indapamide, a thiazide-like diuretic, enhances diuresis and vasodilation, contributing to blood pressure reduction.

Indications for Use

Indications: Co-Prenesa is indicated for the treatment of hypertension to effectively lower blood pressure.

Contraindications

Contraindications: Avoid Co-Prenesa if allergic to any component, history of angioedema from previous ACE inhibitor use, or during pregnancy.

Side Effects

Common side effects may include dizziness, cough, and hypotension. Contact a healthcare provider if experiencing severe side effects.

Usage Instructions

Dosage: The typical dose is one tablet daily, ideally in the morning before eating, swallowed whole with water. Do not crush or chew the tablet.

Benefits Over Analogues

Co-Prenesa has shown superior efficacy in lowering blood pressure and reducing cardiovascular risks compared to individual drug therapies.

Suitable Patient Groups

Co-Prenesa is suitable for adult patients with hypertension. Dosage adjustments may be necessary for elderly individuals or patients with renal impairment.

Storage and Shelf Life

Store Co-Prenesa in a cool, dry place away from sunlight. Check the expiration date on the packaging and do not use expired tablets.

Packaging Description

Each package contains 90 tablets of Co-Prenesa 4 mg/1.25 mg.

Clinical Evidence

Clinical Trials: Clinical trials have demonstrated the effectiveness of Co-Prenesa in reducing blood pressure and cardiovascular events in hypertensive patients.

Additional Information

Additional Recommendations: Regular monitoring of blood pressure and kidney function is crucial during Co-Prenesa therapy to ensure optimal treatment outcomes.