Description
Cordiamin (Nikethamide) Ampoules 2 ml. №10
Composition
Active ingredient: Nikethamide
Mechanism of Action
Nikethamide is a respiratory stimulant that directly stimulates the respiratory center in the brain. It enhances the sensitivity of the respiratory center to carbon dioxide, resulting in improved ventilation.
Pharmacological Properties
Nikethamide exhibits respiratory stimulant properties by acting on the central nervous system. It helps in increasing the respiratory drive and can be beneficial in conditions of respiratory depression.
Indications for Use
Cordiamin (Nikethamide) ampoules are indicated for conditions necessitating the stimulation of the respiratory center, such as respiratory depression induced by drug overdose or anesthesia.
Contraindications
Do not use Cordiamin (Nikethamide) ampoules if:
- You are allergic to Nikethamide or any other components of the product.
- You have severe hypertension or heart disease.
- You are pregnant or breastfeeding without medical advice.
Side Effects
Common side effects of Cordiamin (Nikethamide) may include nausea, vomiting, headache, dizziness, and allergic reactions. Contact a healthcare provider if any adverse reactions occur.
Usage Instructions
Adults: The typical dosage is 1-2 ampoules administered intramuscularly or intravenously. Consult a healthcare professional for personalized dosing guidance.
Administration: Cordiamin (Nikethamide) ampoules should be administered as per healthcare provider’s instructions. Slow injection is recommended to minimize the risk of adverse effects.
Benefits Compared to Analogues
Cordiamin (Nikethamide) offers rapid respiratory stimulation with a well-established safety profile, making it a preferred choice in emergency situations requiring prompt respiratory support.
Suitable Patient Groups
Cordiamin (Nikethamide) can be used in various patient populations, including adults, adolescents, and elderly individuals. However, dosing adjustments may be necessary based on individual patient characteristics and medical history.
Storage and Shelf Life
Store Cordiamin (Nikethamide) ampoules as per the instructions provided on the packaging. Ensure proper storage conditions to maintain the product’s stability and efficacy. Check the expiration date before use.
Packaging Description
Cordiamin (Nikethamide) ampoules are typically packaged in boxes containing 10 ampoules of 2 ml each. The packaging is designed to ensure product integrity and sterility until use.
Clinical Evidence and Proven Effectiveness
Nikethamide has been extensively studied in clinical trials, demonstrating its efficacy in reversing respiratory depression caused by various etiologies. These findings highlight the importance of Nikethamide in emergency and critical care scenarios.
Additional Information
Close monitoring of patients is crucial during and post-administration of Cordiamin (Nikethamide) to promptly address any potential adverse reactions or hypersensitivity. Healthcare providers should be consulted for comprehensive information on product usage and individualized dosing recommendations.