Description

Xarelto (rivaroxaban) Coated Tablets 2.5 mg. №56

Ingredients:

Each coated tablet contains 2.5 mg of rivaroxaban as the active ingredient.

Dosage:

The recommended dosage is one 2.5 mg tablet taken orally once daily with or without food.

Indications:

Xarelto 2.5 mg tablets are indicated for the prevention of venous thromboembolism in adult patients undergoing elective hip or knee replacement surgery.

Contraindications:

Do not use Xarelto if you have active pathological bleeding or if you are allergic to rivaroxaban.

Directions:

Swallow the tablet whole with water. Do not crush, chew, or break the tablet before swallowing.

Pharmacological Properties:

Xarelto contains rivaroxaban, a direct factor Xa inhibitor that selectively blocks the active site of factor Xa, thereby preventing the formation of thrombin and reducing the risk of blood clot formation.

Side Effects:

Common side effects of Xarelto may include bleeding, bruising, and gastrointestinal discomfort. Contact your healthcare provider if you experience any severe or persistent side effects.

Benefits Compared to Analogues:

Xarelto has shown non-inferiority to enoxaparin in preventing venous thromboembolism post-hip replacement surgery with a similar safety profile.

Suitable Patient Groups:

Xarelto is suitable for adult patients undergoing elective hip or knee replacement surgery. Special caution should be exercised in elderly patients and those with renal impairment.

Storage and Shelf Life:

Store Xarelto in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product after the specified date.

Packaging Description:

Xarelto comes in blister packs containing 56 coated tablets of 2.5 mg strength each.

Scientific Evidence:

Rivaroxaban, the active ingredient in Xarelto, has been extensively studied in clinical trials. Research by Eriksson BI et al. has demonstrated the efficacy of rivaroxaban in preventing venous thromboembolism in orthopedic surgery patients. The study showed non-inferiority to enoxaparin with a comparable safety profile.

Additional Information:

It is crucial to adhere to the prescribed dosage and administration instructions for Xarelto to ensure optimal treatment outcomes. In the event of a missed dose, patients should take the tablet as soon as possible on the same day and continue with the regular dosing schedule. Patients should be vigilant for signs of bleeding and promptly seek medical attention if unusual bleeding occurs while taking Xarelto.