Description
Xarelto (Rivaroxaban) Coated Tablets 20 mg. №100
Composition
Active Ingredient: Rivaroxaban.
Other ingredients: Croscarmellose sodium, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium lauryl sulfate.
Mechanism of Action
Pharmacological Effects: Xarelto works by inhibiting Factor Xa, a key component in the coagulation cascade. By blocking Factor Xa, Xarelto prevents the formation of thrombin, thereby reducing the risk of blood clot formation.
Indications for Use
Xarelto 20 mg tablets are indicated for the prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation.
Contraindications
Do not use Xarelto if: you have active pathological bleeding, severe liver disease, or if you are pregnant. Consult your doctor for a full list of contraindications.
Side Effects
Common side effects of Xarelto may include bleeding, bruising, and dizziness. Contact your healthcare provider if you experience any severe or persistent side effects.
Usage Instructions
Recommended Dosage: The usual dose is 20 mg once daily with the evening meal. Consult a healthcare professional for personalized dosing instructions.
Take Xarelto tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with water. Do not crush, chew, or break the tablet.
Benefits Compared to Analogues
Xarelto has been shown to be non-inferior to warfarin in preventing stroke and systemic embolism in patients with atrial fibrillation. It has a rapid onset of action and does not require routine monitoring like warfarin.
Suitable Patient Groups
Xarelto is suitable for adult patients with non-valvular atrial fibrillation. Consult your healthcare provider for guidance on the use of Xarelto in specific patient populations such as children and the elderly.
Storage Conditions and Shelf Life
Store Xarelto in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use Xarelto after the stated shelf life.
Packaging Description
Xarelto is available in blister packs containing 100 coated tablets of 20 mg each. The packaging is designed to ensure the integrity and stability of the tablets until the expiration date.
Clinical Evidence and Proven Effectiveness
Clinical Trials: Clinical trials have demonstrated the efficacy and safety of Xarelto in various patient populations. The ROCKET AF trial compared rivaroxaban with warfarin in patients with atrial fibrillation and showed that rivaroxaban was as effective as warfarin in preventing stroke and systemic embolism, with a lower risk of intracranial hemorrhage.
