Description
Diocor Solo 80 (Valsartan, Hydrochlorothiazide) Coated Tablets 80 mg. №90
Composition
Active ingredients: Valsartan 80 mg, Hydrochlorothiazide 12.5 mg.
Mechanism of Action
Diocor Solo 80 combines the antihypertensive effects of Valsartan and Hydrochlorothiazide. Valsartan is an angiotensin II receptor blocker that inhibits vasoconstriction and aldosterone-secreting effects of angiotensin II. Hydrochlorothiazide is a thiazide diuretic that promotes diuresis by inhibiting sodium reabsorption in the distal convoluted tubule.
Pharmacological Properties
The synergistic action of Valsartan and Hydrochlorothiazide in Diocor Solo 80 results in effective blood pressure reduction through dual mechanisms of vasodilation and diuresis.
Indications for Use
Diocor Solo 80 is indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled on monotherapy with either Valsartan or Hydrochlorothiazide alone.
Contraindications
Do not use Diocor Solo 80 if:
- You are allergic to any of the ingredients.
- You are pregnant or breastfeeding.
- You have severe renal impairment.
Side Effects
Common side effects of Diocor Solo 80 may include dizziness, electrolyte imbalances, hypotension, and renal dysfunction. Monitoring for these adverse effects is essential during therapy.
Usage Instructions
Recommended dosage: One tablet daily or as directed by a healthcare professional. Swallow the tablet whole with a glass of water. It can be taken with or without food. Do not crush or chew the tablet.
Benefits Compared to Analogues
Diocor Solo 80 offers the advantage of dual therapy with Valsartan and Hydrochlorothiazide, providing superior blood pressure control compared to monotherapy with either component alone. The combination therapy reduces cardiovascular risk and enhances overall efficacy in hypertension management.
Suitable Patient Groups
Diocor Solo 80 is suitable for adult patients with uncontrolled hypertension who require dual therapy for optimal blood pressure management. Caution is advised in the elderly and those with renal impairment due to the potential for side effects.
Storage Conditions and Shelf Life
Store Diocor Solo 80 in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect from moisture. Check the expiration date on the packaging and do not use after the specified shelf life.
Packaging Description
Each pack of Diocor Solo 80 contains 90 coated tablets of 80 mg strength. The packaging is designed to maintain the stability and integrity of the tablets throughout the shelf life.
Clinical Evidence and Proven Effectiveness
Studies have shown that the combination of Valsartan and Hydrochlorothiazide in Diocor Solo 80 effectively lowers blood pressure in hypertensive patients. Valsartan blocks angiotensin II receptors, while Hydrochlorothiazide promotes diuresis, resulting in enhanced antihypertensive effects.
Clinical trials have demonstrated that the dual therapy of Valsartan and Hydrochlorothiazide in Diocor Solo 80 is more effective in blood pressure control than monotherapy with either drug alone. The combination therapy offers improved cardiovascular protection and reduced risk of hypertension-related complications.
