Description
Disgren (triflusal) Capsules 300 mg. №30
Composition:
Each capsule contains 300 mg of triflusal as the active ingredient.
Mechanism of Action:
Triflusal, a platelet aggregation inhibitor, works by preventing the formation of blood clots.
Pharmacological Properties:
Triflusal exerts its antiplatelet effects by inhibiting thromboxane A2 synthesis, thereby reducing platelet aggregation.
Indications for Use:
Disgren capsules are indicated for the prevention of thrombotic events in patients with a history of myocardial infarction or unstable angina.
Contraindications:
Avoid using Disgren capsules if you have a known hypersensitivity to triflusal or any other component of the product.
Side Effects:
Common side effects may include gastrointestinal disturbances, such as dyspepsia and gastritis. In rare cases, allergic reactions like rash or angioedema may occur.
Usage Instructions:
The recommended dosage is one 300 mg capsule daily, to be taken orally with food. Swallow the capsule whole with a full glass of water. Do not crush or chew the capsule.
Benefits Compared to Analogues:
Triflusal has shown similar efficacy to aspirin in preventing thrombotic events but with a lower incidence of gastrointestinal side effects, making it a favorable option for patients at risk.
Suitable Patient Groups:
Disgren capsules are suitable for adult patients, including the elderly population, with a history of myocardial infarction or unstable angina.
Storage and Shelf Life:
Store Disgren capsules in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond that date.
Packaging Description:
Disgren capsules are available in a pack of 30 capsules, each containing 300 mg of triflusal.
Clinical Evidence and Proven Effectiveness:
Triflusal has been studied extensively for its efficacy in preventing thrombotic events. Clinical trials have demonstrated its effectiveness in reducing the risk of recurrent cardiovascular events in high-risk patients. In comparative studies with aspirin, triflusal showed similar efficacy with a more favorable gastrointestinal side effect profile.