Description

Eroton (Sildenafil) Tablets 50 mg. №4

Composition

Active Ingredient: Each tablet contains 50 mg of sildenafil citrate.

Mechanism of Action

Sildenafil, the active ingredient in Eroton, acts as a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) enzyme. Inhibition of PDE5 leads to prolonged relaxation of smooth muscle cells in the corpus cavernosum of the penis, resulting in increased blood flow and thus facilitating an erection during sexual stimulation.

Pharmacological Properties

Sildenafil citrate is a potent and selective inhibitor of PDE5. It enhances the vasodilatory effects of nitric oxide released during sexual stimulation by inhibiting PDE5, which is responsible for the degradation of cGMP in the corpus cavernosum. This mechanism results in increased levels of cGMP, smooth muscle relaxation, and improved penile blood flow.

Indications for Use

Indications: Eroton tablets are indicated for the treatment of erectile dysfunction in adult men, a condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance.

Contraindications

Contraindications: Eroton tablets should not be taken by individuals with a known hypersensitivity to sildenafil or any other component of the formulation. Concomitant use of nitrates or nitric oxide donors is contraindicated due to the potential for severe hypotension.

Side Effects

• Common Side Effects: Adverse reactions associated with Eroton may include headache, facial flushing, dyspepsia, and nasal congestion. In rare cases, serious side effects such as priapism (prolonged erection exceeding 4 hours) and cardiovascular events like chest pain have been reported. Immediate medical attention is necessary in the event of such occurrences.

Usage Instructions

Dosage: The recommended dose is one 50 mg tablet taken orally approximately 30 minutes to 1 hour before anticipated sexual activity. It is important not to exceed a maximum dose of one tablet per 24-hour period to minimize the risk of adverse effects.

Benefits Compared to Analogues

Eroton, containing sildenafil citrate as the active ingredient, offers a well-established and clinically proven treatment option for erectile dysfunction. Compared to other phosphodiesterase inhibitors, sildenafil has a rapid onset of action, high efficacy rates, and a favorable safety profile when used as directed.

Suitable Patient Groups

Eroton is intended for adult men diagnosed with erectile dysfunction. It is not indicated for use in women, children, or adolescents under the age of 18 years. Special caution should be exercised in elderly patients or individuals with underlying cardiovascular conditions, as they may be more susceptible to potential cardiovascular effects of sildenafil.

Storage and Shelf Life

• Storage: Eroton tablets should be stored at room temperature (15-30°C) in a dry place away from direct sunlight and moisture. Avoid storing the medication in the bathroom or kitchen where humidity levels may be higher.
• Shelf Life: The shelf life of Eroton tablets is typically 2 years from the date of manufacture. Discard any expired or unused tablets properly according to local regulations.

Packaging Description

Eroton tablets are typically packaged in blister packs to ensure individual tablet integrity and protection from external factors. Each pack contains 4 tablets, each imprinted with the dosage strength for easy identification.