Description
Farmazolin N (Xylometazoline Hydrochloride) Nasal Spray 1 mg/ml. 15 ml
Ingredients
Active ingredient: Xylometazoline hydrochloride. Inactive ingredients: benzalkonium chloride, sodium dihydrogen phosphate dihydrate, disodium phosphate dodecahydrate, sorbitol, hypromellose, and purified water.
Mechanism of Action
Xylometazoline hydrochloride, the active ingredient in Farmazolin N, is a potent vasoconstrictor that acts on alpha-adrenergic receptors in the nasal mucosa. This action leads to the constriction of blood vessels, reducing nasal congestion and swelling.
Pharmacological Properties
The vasoconstrictive properties of xylometazoline hydrochloride result in the reduction of nasal blood flow, thereby decreasing nasal congestion. This mechanism of action provides rapid relief from nasal congestion with a duration of action of up to 12 hours.
Indications for Use
Farmazolin N Nasal Spray is indicated for the relief of nasal congestion associated with hay fever, sinusitis, and other upper respiratory allergies.
Contraindications
Contraindications: Do not use in children under 12 years of age. Avoid in case of hypersensitivity to xylometazoline or any other ingredients in the product.
Side Effects
Common side effects may include nasal dryness, irritation, or sneezing. Rarely, systemic effects such as palpitations or increased blood pressure may occur. Discontinue use if any adverse reactions develop.
Usage Instructions
Shake well before use. Clear nasal passages before application. Insert the nozzle into each nostril and spray as directed. Avoid inhaling deeply. Adults and children over 12 years: 1-2 sprays into each nostril every 10-12 hours. Do not exceed 2 applications in 24 hours.
Benefits Compared to Analogues
Xylometazoline has demonstrated comparable effectiveness to other nasal decongestants with a favorable safety profile. Farmazolin N Nasal Spray provides a convenient and reliable solution for nasal congestion associated with allergies and sinusitis.
Suitable Patient Groups
This product is suitable for adults and children over 12 years of age. It is not recommended for use in children under 12 years without medical supervision.
Storage and Shelf Life
Store in a cool, dry place away from direct sunlight. Do not freeze. Keep out of reach of children. The shelf life of Farmazolin N Nasal Spray is typically 24 months from the date of manufacture.
Packaging Description
Farmazolin N Nasal Spray is available in a 15 ml bottle with a nasal spray pump for easy and accurate dosing.
Scientific Evidence
Research has demonstrated the efficacy of xylometazoline in providing relief from nasal congestion in various clinical trials. A study by Eccles et al. (2007) highlighted the rapid onset of action and long-lasting effects of xylometazoline, making it a preferred choice for nasal congestion relief.
