Description
Glicin V Tablets 250 mg. №50
Ingredients
Each tablet contains 250 mg of Gliclazide.
Mechanism of Action
Gliclazide, the active ingredient in Glicin V tablets, is a sulfonylurea that stimulates insulin release from the pancreas, lowering blood sugar levels in patients with type 2 diabetes mellitus.
Pharmacological Properties
Gliclazide acts by binding to specific receptors on pancreatic beta cells, leading to the closure of ATP-sensitive potassium channels and subsequent depolarization of the cell membrane. This triggers calcium influx and insulin release, promoting glucose utilization and reducing hyperglycemia.
Indications for Use
Glicin V tablets are indicated for the treatment of type 2 diabetes mellitus to help control blood glucose levels.
Contraindications
Avoid using Glicin V tablets if you have a known allergy to sulfonylureas or any components of the tablets. Consult a healthcare professional for suitable alternatives.
Side Effects
- Hypoglycemia
- Gastrointestinal disturbances
- Skin reactions
Usage Instructions
The recommended dosage is one tablet daily, preferably taken with breakfast or the first main meal of the day. Follow the instructions of your healthcare provider for personalized dosing.
Benefits Compared to Analogues
Gliclazide has demonstrated efficacy in reducing HbA1c levels with a lower risk of hypoglycemia compared to other sulfonylureas, making it a favorable choice for diabetes management.
Suitable Patient Groups
Glicin V tablets are suitable for adult patients with type 2 diabetes mellitus. Dosage adjustments may be necessary for elderly individuals or those with renal or hepatic impairment.
Storage and Shelf Life
Store Glicin V tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use expired tablets.
Packaging Description
Glicin V tablets are available in a pack containing 50 tablets, each with a dosage of 250 mg of Gliclazide. The packaging is designed to maintain the integrity and potency of the tablets.
Clinical Evidence and Proven Effectiveness
Gliclazide has been extensively studied for its efficacy in managing type 2 diabetes mellitus. Clinical studies have shown that Gliclazide effectively reduces blood glucose levels and HbA1c, contributing to improved glycemic control.
Research published in the International Journal of Clinical Practice has highlighted the favorable risk-benefit profile of Gliclazide, emphasizing its role in achieving optimal diabetes management with a reduced risk of hypoglycemia.
