Description
Prilamid Tablets: Overview
Ingredients
- Active ingredients: Perindopril 2 mg and Indapamide 0.625 mg.
Dosage
- Dosage: The usual dose is one tablet taken once daily, preferably in the morning.
Indications
- Indications: Prilamid tablets are used to treat hypertension and lower blood pressure.
Contraindications
- Contraindications: Avoid Prilamid if allergic to perindopril, indapamide, or any other ingredients.
Directions
- Directions: Swallow the tablet whole with water, with or without food.
Scientific Evidence
Prilamid combines perindopril, an ACE inhibitor, with indapamide, a diuretic, to lower blood pressure. Perindopril inhibits the angiotensin-converting enzyme, leading to vasodilation and reduced aldosterone secretion. Indapamide promotes diuresis and vasodilation. Studies show this combination is more effective in reducing blood pressure than either drug alone.
Additional Information
- Storage: Keep Prilamid at room temperature away from moisture and heat.
- Monitoring: Regularly check blood pressure while using this medication.
- Interactions: Inform your doctor about other medications or supplements you are taking to avoid interactions.
Pharmacological Effects: Perindopril and indapamide work together to lower blood pressure by reducing peripheral resistance and promoting diuresis, aiding in managing hypertension and reducing cardiovascular risks.
Clinical Trials: Studies have shown the efficacy of Prilamid in lowering blood pressure and improving cardiovascular outcomes. Research by Williams et al. (2016) demonstrated a significant reduction in both systolic and diastolic blood pressure with the combination therapy of perindopril and indapamide compared to monotherapy.
