Description

Alfirum (alfuzosin) tablets with modified release 10 mg. №30

Ingredients

Active ingredient: Alfuzosin hydrochloride 10 mg.
Other ingredients: lactose monohydrate, hypromellose, colloidal anhydrous silica, magnesium stearate, macrogol, talc, titanium dioxide (E171), iron oxide yellow (E172).

Dosage

Recommended dosage: 1 tablet daily, swallowed whole with a glass of water after the same meal each day. Do not crush or chew the tablet.

Indications

Alfirum (alfuzosin) tablets are indicated for the treatment of benign prostatic hyperplasia (BPH) to improve symptoms such as difficulty urinating, weak stream, and frequent urination.

Contraindications

Do not use Alfirum (alfuzosin) tablets if you have severe liver impairment, hypotension, or a history of orthostatic reactions. Avoid concomitant use with potent CYP3A4 inhibitors.

Directions

Take Alfirum (alfuzosin) tablets exactly as prescribed by your healthcare provider. Follow all instructions on the prescription label. Do not take in larger or smaller amounts or for longer than recommended.

Scientific Evidence

Alfuzosin, the active ingredient in Alfirum tablets, is a selective antagonist of post-synaptic alpha1-adrenoreceptors in the lower urinary tract. Studies have shown that alfuzosin effectively improves urinary symptoms associated with BPH by relaxing smooth muscle in the prostate and bladder neck, leading to improved urine flow and reduced symptoms.

Additional Information

It is important to note that Alfirum (alfuzosin) tablets with modified release 10 mg should be used with caution in patients with moderate hepatic impairment and in the elderly. Common side effects may include dizziness, headache, and fatigue. Contact your doctor if you experience severe dizziness or fainting while taking this medication.

Alfuzosin has been extensively studied in clinical trials, demonstrating its efficacy and safety in the management of BPH symptoms. Research published in the Journal of Urology has highlighted the positive outcomes of alfuzosin therapy in improving urinary flow rates and quality of life in patients with BPH.

Compared to other alpha-blockers, alfuzosin has shown similar efficacy in relieving BPH symptoms with a lower risk of cardiovascular side effects. This makes Alfirum tablets a favorable choice for patients requiring long-term treatment for benign prostatic hyperplasia.