Description
Amigren (Sumatriptan) Capsules 100 mg. №1
Composition
Each capsule contains 100 mg of sumatriptan.
Mechanism of Action
Sumatriptan, the active ingredient in Amigren capsules, is a selective serotonin receptor agonist. It acts by constricting blood vessels in the brain, thereby reducing the pain associated with migraines.
Pharmacological Properties
Sumatriptan exhibits its therapeutic effects by targeting specific serotonin receptors, leading to vasoconstriction in the cranial blood vessels. This action helps alleviate the symptoms of migraines.
Indications for Use
Amigren capsules are indicated for the acute treatment of migraine attacks, with or without aura.
Contraindications
Avoid using Amigren capsules if you have uncontrolled hypertension, ischemic heart disease, or have taken MAO inhibitors within the past 14 days.
Side Effects
Common side effects of Amigren may include chest pain, tightness in the chest or throat, dizziness, and drowsiness. If any severe side effects occur, seek immediate medical attention.
Usage Instructions
The recommended dosage is one capsule (100 mg) at the onset of a migraine headache. Do not exceed more than 200 mg within a 24-hour period. Swallow the capsule whole with water; do not crush, chew, or break it.
Benefits Compared to Analogues
Amigren has shown superior efficacy in relieving migraine symptoms compared to other commonly used migraine medications. It provides faster and more sustained relief from migraine pain, as supported by clinical studies.
Suitable Patient Groups
Amigren is suitable for adults experiencing migraine attacks. Consult a healthcare provider for appropriate dosing in special populations such as children, the elderly, or individuals with specific medical conditions.
Storage and Shelf Life
- Store the capsules at room temperature, away from moisture and heat, to maintain their stability.
Packaging Description
Amigren capsules are typically packaged in blister packs to ensure individual dosing convenience and product protection.
Clinical Evidence and Proven Effectiveness
Sumatriptan, the active component of Amigren capsules, has been extensively studied for its efficacy in treating migraines. Clinical studies have consistently shown that sumatriptan effectively relieves migraine symptoms, including pain, nausea, and sensitivity to light and sound.
For instance, a study published in the journal Headache compared sumatriptan’s effectiveness with other migraine medications and concluded that sumatriptan provided rapid and sustained relief from migraine pain, highlighting its clinical benefits.
