Description
Amiokordin (Amiodarone Hydrochloride) Tablets 200 mg. №30
Ingredients:
Each tablet contains 200 mg of amiodarone hydrochloride.
Mechanism of Action:
Amiodarone exerts its pharmacological effects by blocking potassium channels in the heart, prolonging the action potential duration and refractory period. This action helps in stabilizing the heart’s electrical activity and preventing the occurrence of abnormal rhythms.
Pharmacological Properties:
Amiokordin has potent antiarrhythmic properties due to its ability to modulate cardiac ion channels, resulting in the normalization of heart rhythm.
Indications for Use:
Amiokordin is indicated for the treatment of various types of irregular heartbeats (arrhythmias). It is particularly effective in managing ventricular arrhythmias.
Contraindications:
Do not use Amiokordin if you have a known hypersensitivity to amiodarone or any of the tablet’s components. It is also contraindicated in patients with severe sinus-node dysfunction, severe bradycardia, and certain types of heart block.
Side Effects:
Common side effects of Amiokordin may include nausea, vomiting, fatigue, and visual disturbances. Serious side effects such as pulmonary toxicity and thyroid dysfunction may also occur.
Usage Instructions:
The usual adult dose is 200-400 mg daily, taken as a single dose or divided into smaller doses. Take Amiokordin exactly as prescribed by your healthcare provider. It is usually taken with food to improve absorption. Do not crush or chew the tablets.
Benefits Compared to Analogues:
Amiokordin has shown superior efficacy in managing arrhythmias compared to other antiarrhythmic drugs. Its lower risk of proarrhythmia makes it a preferred choice in the treatment of certain cardiac conditions.
Suitable Patient Groups:
Amiokordin can be used in adult patients for the management of arrhythmias. Dosing adjustments may be necessary in elderly patients or those with hepatic impairment. It is not recommended for use in children.
Storage Conditions and Shelf Life:
Store Amiokordin in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use the product after it has expired.
Packaging Description:
Amiokordin tablets are packed in a blister pack to ensure individual tablet protection. Each pack contains 30 tablets of 200 mg strength.
Clinical Evidence and Proven Effectiveness:
Amiokordin (amiodarone hydrochloride) has been extensively studied for its efficacy in managing various arrhythmias. Research published in the Journal of the American College of Cardiology demonstrated the superior effectiveness of amiodarone in reducing the recurrence of ventricular arrhythmias compared to other antiarrhythmic drugs.
Additional Information:
It is important to regularly monitor thyroid function, liver enzymes, and lung function while taking Amiokordin, as the medication can affect these organ systems. Consult your healthcare provider if you experience any unusual symptoms while on this medication.
