$8.00
Manufacturer: Ukraine
Description
Ingredients
active ingredient: amizon (enisamium iodide);
1 tablet contains amizon (enisamium iodide) 125 mg (0.125 g) or 250 mg (0.25 g);
excipients: lactose monohydrate, microcrystalline cellulose, povidone, croscarmellose sodium, calcium stearate;
sheath: OPADRY II Clear 85F19250 (polyethylene glycol, polysorbate 80, polyvinyl alcohol, talc).
Dosage form
Coated tablets.
Basic physical and chemical properties: tablets are round, biconvex, yellow or yellow-green, film-coated. Minor inclusions are allowed on the surface of the core tablets.
Pharmacotherapeutic group
Antiviral agents for systemic use. Antivirals of direct action.
ATX code J05 A X.
Pharmacodynamics
Amizon is a derivative of isonicotinic acid. It has an inhibitory effect on influenza viruses, has interferonogenic properties, increases the body’s resistance to viral infections, has anti-inflammatory, antipyretic and analgesic effects.
The antiviral effect of Amizon is associated with its direct effect on the hemagglutinins of the influenza virus, as a result of which the virion loses its ability to attach to target cells for further replication.
The anti-inflammatory effect is the result of stabilization of cell and lysosomal membranes, slowing down the degranulation of basophils, antioxidant action, normalization of the level of prostaglandins, cyclic nucleotides and energy metabolism in the focus of inflammation. The antipyretic properties of this remedy are due to the effect on the thermoregulatory centers of the brain. The analgesic effect of the drug is carried out through the reticular formation of the brain stem.
Amizon enhances persistent immunity by increasing the level of endogenous interferon in blood plasma by 3-4 times, lysozyme and increasing the titer of antibodies to infectious agents, as well as cellular immunity – by stimulating the functional activity of T-lymphocytes and macrophages. This tool is a powerful inducer of endogenous interferon.
Indications
- Treatment and prevention of diseases: influenza and respiratory viral infections;
- treatment of measles, rubella, chicken pox, mumps infection;
- as part of the complex therapy of viral, viral-bacterial and bacterial pneumonia and tonsillitis.
Contraindications
- Hypersensitivity to iodine preparations and other components of the drug;
- the presence of allergic reactions, regardless of the nature of the allergen in history;
- severe organic lesions of the liver and kidneys;
- tuberculosis;
- dermatitis herpetiformis Dühring (Dühring-Brock syndrome);
- manifest and latent hyperthyroidism;
- autonomous thyroid adenoma, focal and diffuse autonomous thyroid lesions;
- hemorrhagic diathesis.
Directions
Amizon (enisamium iodide) is taken orally after meals, without chewing. The maximum single dose is 1000 mg, the daily dose is 2000 mg. The recommended course of treatment, depending on the severity and etiology of the disease, is from 5 to 30 days.
Influenza and other respiratory viral infections
Treatment. Adults and children from 12 years of age are prescribed 250-500 mg 2-4 times a day for 5-7 days; children from 6 to 12 years of age should be prescribed 125 mg 2-3 times a day for 5-7 days.
Prevention. Adults and children from 16 years old – 250 mg per day for 3-5 days, then – 250 mg 1 time in 2-3 days for 2-3 weeks; children 6-12 years old – 125 mg every other day for 2-3 weeks; children from 12 to 16 years old – 250 mg every other day for 2-3 weeks.
For the treatment of measles, rubella, chicken pox, adults and children over 16 years of age – 500 mg 3 times a day; children 6-7 years old – 125 mg 3 times a day; children 8-12 years old – 125 mg 4 times a day; children 13-14 years old – 250 mg 3 times a day; children 14-16 years old – 250 mg 4 times a day.
For the treatment of mumps infection in adults and children over 14 years of age, prescribe 250 mg 4 times a day for moderate disease and 500 mg 3 times a day for severe disease for 6-7 days; children aged 12-14 years should be prescribed 250 mg 3-4 times a day for 6-7 days.
In the complex therapy of pneumonia for adults – 250 mg 3 times a day for 10-15 days.
In the complex therapy of angina for adults – 250 mg 3-4 times a day for 5 days with moderate severity of the disease; 500 mg 3-4 times a day for 7 days in severe disease.
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