Amoxil (amoxicillin) tablets 500 mg. №20

Amoxil (amoxicillin) tablets 500 mg. №20

$12.90

Manufacturer: Ukraine

Amoxicillin is a semi-synthetic aminopenicillin antibiotic with a broad spectrum of action for oral use. Suppresses the synthesis of the cell wall of bacteria. It has a wide range of antimicrobial activity.

The following types of microorganisms are sensitive to the drug:

  • gram-positive aerobes: Corinebacterium diphteriae, Enterococcus faecalis, Listeria monocytogenes, Streptococcus agalactiae, Streptococcus bovis, Streptococcus pyogenes;
  • gram-negative aerobes: Helicobacter pylori;
  • anaerobes: Peptostreptococci;
  • others: Borrelia.

Intermittently sensitive (acquired resistance can complicate treatment): Corinebacterium spp., Enterococcus faecium, Streptococcus pneumoniae, Streptococcus viridans, Escherichia coli, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Proteus mirabilis, Prevotella, Fusobacterium spp. 

Category:

Description

Ingredients

active substance: amoxicillin;

1 tablet contains amoxicillin trihydrate, in terms of amoxicillin – 500 mg;

excipients: sodium starch glycolate (type A), povidone, calcium stearate.

Medicinal form

Tablets.

The main physicochemical properties: tablets are white with a yellowish tinge, flat-cylindrical with a bevel and a line.

Pharmacotherapeutic group

Antibacterial agents for systemic use. Beta-lactam antibiotics, penicillins. ATX code J01C A04.

Pharmacodynamics

Amoxicillin is a semi-synthetic aminopenicillin antibiotic with a broad spectrum of action for oral use. Suppresses the synthesis of the cell wall of bacteria. It has a wide range of antimicrobial activity.

The following types of microorganisms are sensitive to the drug:

  • gram-positive aerobes: Corinebacterium diphteriae, Enterococcus faecalis, Listeria monocytogenes, Streptococcus agalactiae, Streptococcus bovis, Streptococcus pyogenes;
  • gram-negative aerobes: Helicobacter pylori;
  • anaerobes: Peptostreptococci;
  • others: Borrelia.

Intermittently sensitive (acquired resistance can complicate treatment): Corinebacterium spp., Enterococcus faecium, Streptococcus pneumoniae, Streptococcus viridans, Escherichia coli, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Proteus mirabilis, Prevotella, Fusobacterium spp. 

Such resistant species as: Staphylococcus aureus, Acinetobacter, Citrobacter, Enterobacter, Klebsiella, Legionella, Morganella morganii, Proteus vulgaris, Providencia, Pseudomonas, Serratia, Bacteroides fragilis, Chlamidia, Mycoplasma, Rickettsia. 

Indications

Infections of the respiratory organs, genitourinary system, digestive tract (including in combination with metronidazole or clarithromycin used to treat diseases associated with Helicobacter pylori), skin and soft tissues, caused by microorganisms sensitive to the drug.

Contraindications

Hypersensitivity to any components of the drug and/or to any antibacterial agents of the penicillin group.

History of severe hypersensitivity reactions (including anaphylaxis) associated with the use of other beta-lactam agents (including cephalosporins, carbapenems or monobactams).

Infectious mononucleosis and leukemoid reactions of the lymphatic type.

Dosage and Administration

The range of doses when using Amoxicillin tablets is very wide. The doctor sets the dose, frequency of administration and duration of treatment individually.

Adults and children with a body weight of more than 40 kg should take from 250 mg to 500 mg of the drug Amoxil three times a day or from 500 mg to 1000 mg twice a day. For sinusitis, pneumonia and other severe infections, 500 mg to 1000 mg should be taken three times a day. The daily dose can be increased to a maximum of 6 g.

Children with a body weight of less than 40 kg usually take 40-90 mg/kg/day of Amoxil® daily in three doses or from 25 mg to 45 mg/kg/day in two doses. The maximum daily dose for children is 100 mg/kg of body weight.

In the case of mild and moderate infection, the drug should be taken for 5-7 days. However, in the case of infections caused by streptococcus, the duration of treatment should be at least 10 days.

In the treatment of chronic diseases, local infectious lesions, infections with a severe course, doses of the drug should be determined taking into account the clinical picture of the disease.

Taking the drug should be continued for 48 hours after the symptoms of the disease disappear.

Amoxicillin tablets can be used in patients with renal failure. With severe renal failure (creatinine clearance < 10 ml/min, i.e. 0.16 ml/s), drug dosing intervals should be 12-24 hours, and the drug dose should be reduced by 15-50%.

In case of impaired liver function, a change in dosage is not required.

Amoxicillin tablets can be taken regardless of meals. The tablet should be swallowed with liquid. During treatment with Amoxil, the patient is recommended to drink more liquid than usual.

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