$6.00
Manufacturer: Ukraine
Indicated for:
Prevention of the development of iodine deficiency.
Prevention of recurrence of iodine-deficient goiter after surgical removal, as well as after the completion of complex treatment with thyroid hormone preparations.
Treatment of diffuse euthyroid goiter.
Description
Ingredients
active ingredient: potassium iodide;
1 tablet contains: potassium iodide 1 mg;
excipients: crystalline sugar, calcium stearate.
Dosage form
Pills.
Basic physical and chemical properties: tablets of white or almost white color with a yellowish tint, flat-cylindrical shape with a chamfer.
Pharmacotherapeutic group
Iodine preparations used in diseases of the thyroid gland. ATX code H03C A.
Pharmacodynamics
Iodine is a vital trace element that is part of the thyroid hormones – thyroxine (T4) and triiodothyronine (T3), which ensures its normal functioning.
When iodides enter the epithelial cells of the thyroid gland follicles, under the influence of the enzyme iodide peroxidase, iodine is oxidized to form elemental iodine. The substance enters into a substitution reaction with the aromatic cycle of tyrosine, resulting in the formation of thyronines: a 3,5-iodine derivative (the hormone thyroxine – T4) and a 3-iodine derivative (the hormone triiodothyronine – T3). Thyronins form a complex with thyroglobulin protein, which is deposited in the colloid of the thyroid follicle and remains in this state for several days and weeks. With iodine deficiency, this process is disrupted. Iodine, which enters the body in physiological quantities, prevents the development of endemic goiter associated with a lack of this element in food; normalizes the size of the thyroid gland in adult patients; affects the ratio of T3 / T4.
Indications
Prevention of the development of iodine deficiency.
Prevention of recurrence of iodine-deficient goiter after surgical removal, as well as after the completion of complex treatment with thyroid hormone preparations.
Treatment of diffuse euthyroid goiter.
Contraindications
Hypersensitivity to iodine or one of the other components of the drug. Manifest hyperthyroidism. The use of potassium iodide in doses exceeding 150 mcg of iodine per day in latent hyperthyroidism. The use of potassium iodide in doses of 300 to 1000 μg of iodine per day for autonomous adenoma, focal and diffuse autonomous thyroid lesions, with the exception of preoperative iodine therapy for the purpose of blockade of the thyroid gland according to Plumer. Pulmonary tuberculosis. Hemorrhagic diathesis. Dermatitis herpetiformis Dühring (Dühring-Brock syndrome).
Dosage and administration
Antistrumin-Darnitsa for adults and children over the age of 12 years should be taken orally after meals, 1 tablet (1 mg of potassium iodide) once every 7 days, drinking plenty of liquid, while prevention can last up to several years.
In the treatment of diffuse forms of goiter, the daily dose for adults and children from 12 years of age is 1 tablet, the drug is taken 2-3 times a week.
It usually takes 6 to 12 months or more to treat goiter in adults and children over 12 years of age.
In general, the question of the dosage and duration of the drug for preventive measures or for the treatment of thyroid diseases is decided by the doctor on an individual basis.
To prevent irritation of the mucous membrane of the digestive tract, drink the drug with milk, jelly or sweet tea.
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