$17.00
Manufacturer: Canada
Description
Ingredients
active ingredient: acetylsalicylic acid;
1 tablet contains 80 mg of acetylsalicylic acid;
excipients: mannitol (E 421), sodium saccharin, corn starch, stearic acid, orange flavor, dye FD & C red No. 40 lacquer 14% (E 129), quinoline yellow dye (E 104).
Dosage form
Chewable tablets.
Basic physical and chemical properties: orange-pink, round, biconvex with an imprint of “ASA 80” on one side and a score line on the other.
Pharmacotherapeutic group
Analgesics and antipyretics. ATX code N02B A01.
Pharmacodynamics
Acetylsalicylic acid has an antiplatelet effect, reduces platelet activity through the suppression of the formation of thromboxane A2 by acetylation of platelet cyclooxygenase.
This inhibitory effect is especially pronounced for platelets, since they are not capable of resynthesis of this enzyme. Acetylsalicylic acid also has other inhibitory effects on platelets. In connection with these effects, it is used in many vascular diseases.
Acetylsalicylic acid belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs), has anti-inflammatory, antipyretic and analgesic effects, which is associated with inhibition of prostaglandin synthesis. The antipyretic effect is associated with the effect on the hypothalamic centers of thermoregulation. The analgesic effect is due to the effect on the centers of pain sensitivity.
Indications
- Prevention of cerebrovascular accidents, secondary prevention of myocardial infarction and unstable angina in adults.
- Pain syndrome of various origins, fever.
Contraindications
- Hypersensitivity to acetylsalicylic acid, other salicylates, non-steroidal anti-inflammatory drugs, analgesics, antipyretics or any component of Asafen (acetylsalicylic acid) 80 mg.
- Asthma caused by taking salicylates or substances with a similar effect, especially NSAIDs in history.
- Acute peptic ulcers.
- History of peptic ulcers.
- Hemorrhagic diathesis.
- Severe renal failure.
- Severe liver failure.
- Severe heart failure.
- Combination with methotrexate at a dose of 15 mg/week or more.
- Last trimester of pregnancy.
Dosage and administration
Asafen (acetylsalicylic acid) 80 mg. is taken orally after a meal, the tablet should be chewed and washed down with a sufficient amount of water or other liquid.
Prevention of cerebrovascular accidents, secondary prevention of myocardial infarction and unstable angina pectoris: 80-320 mg per day in 1-3 doses.
Acetylsalicylic acid is intended for long-term use, the duration of therapy is determined by the doctor individually. Self-medication is risky, the prescription of the drug has its own peculiarities.
Pain syndrome of various origins, fever.
The duration of use as an analgesic and antipyretic agent is no more than 3-5 days.
Adults : 320-640 mg 4-6 times a day, depending on the need.
The maximum daily dose is 3-4 g.
Children over the age of 16: 10-15 mg per 1 kg of body weight per day every 4 hours, depending on the need. The maximum daily dose is 65 mg / kg of body weight, but not more than the maximum dose for adults.
Due to the fact that the tablets do not have an enteric coating, in order to prevent the occurrence of a hypersensitivity reaction and erosive and ulcerative lesions, it is necessary to take drugs that reduce secretion (omeprazole, antacids) or have a gastroprotective effect (quercetin) an hour before taking Asafen (acetylsalicylic acid) 80 mg..
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