Description

Atacand (candesartan cilexetil) tablets 16 mg. №28

Ingredients

Active ingredient: Candesartan cilexetil 16 mg.

Dosage

Dosage: The usual recommended dose is 16 mg once daily. Dosage may be increased to a maximum of 32 mg once daily based on blood pressure response.

Indications

Indications: Atacand is indicated for the treatment of hypertension in adults and children aged 1 to 17 years.

Contraindications

Contraindications: Do not use Atacand if you are pregnant, have severe liver disease, or have a history of angioedema with previous use of ACE inhibitors.

Directions

Directions: Take Atacand exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water.

Scientific Evidence

Atacand (candesartan cilexetil) is a selective angiotensin II receptor blocker that effectively lowers blood pressure by blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Studies have shown that candesartan cilexetil is well-tolerated and provides significant blood pressure reduction in hypertensive patients.

Additional Information

It is important to regularly monitor blood pressure levels while taking Atacand to ensure optimal control. Inform your healthcare provider about any other medications or supplements you are taking to avoid potential drug interactions.

Pharmacological Effects

Candesartan cilexetil works by selectively blocking the angiotensin II receptor subtype AT1. By inhibiting the vasoconstrictor and aldosterone-secreting effects of angiotensin II, it leads to vasodilation and decreased secretion of aldosterone, resulting in lowered blood pressure.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of candesartan cilexetil in reducing blood pressure and improving cardiovascular outcomes. In comparative studies, candesartan has shown similar effectiveness to other antihypertensive agents with a favorable side effect profile.

Overall, Atacand (candesartan cilexetil) tablets 16 mg. №28 offer a well-established treatment option for hypertension with proven efficacy and tolerability.