Description
Caduet (Amlodipine and Atorvastatin) Coated Tablets 10 mg/10 mg. №30
Ingredients
Each tablet contains 10 mg of amlodipine besylate and 10 mg of atorvastatin calcium.
Mechanism of Action
Caduet works by relaxing blood vessels and improving blood flow. Amlodipine, a calcium channel blocker, inhibits calcium entry into smooth muscle cells, leading to vasodilation. Atorvastatin, a statin, blocks cholesterol synthesis by inhibiting the enzyme responsible in the liver.
Pharmacological Properties
The combination of amlodipine and atorvastatin in Caduet synergistically lowers blood pressure and cholesterol levels, respectively, by their distinct mechanisms of action.
Indications for Use
Caduet is indicated for the treatment of hypertension and dyslipidemia to reduce blood pressure and cholesterol levels.
Contraindications
Avoid Caduet if pregnant, breastfeeding, or with liver disease. Consult your healthcare provider regarding your medical history before starting this medication.
Side Effects
Possible side effects of Caduet include dizziness, muscle pain, and liver issues. Notify your healthcare provider of any unusual symptoms.
Usage Instructions
The recommended dosage is one tablet daily, to be taken consistently at the same time each day as prescribed by your doctor. Caduet can be taken with or without food.
Benefits Compared to Analogues
Caduet has demonstrated comparable or superior efficacy in managing hypertension and dyslipidemia compared to other antihypertensive and lipid-lowering medications. The convenience of a single tablet combination therapy enhances patient adherence to treatment regimens.
Suitable Patient Groups
Caduet is suitable for adult patients with hypertension and dyslipidemia. Dosage adjustments may be necessary for specific patient populations such as children and the elderly; consult a healthcare provider for individualized recommendations.
Storage and Shelf Life
Store Caduet in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond its shelf life.
Packaging Description
Caduet is available in packages containing 30 coated tablets, each with a dosage of 10 mg amlodipine and 10 mg atorvastatin.
Clinical Evidence and Proven Effectiveness
Studies have shown that the combination of amlodipine and atorvastatin in Caduet effectively lowers blood pressure and cholesterol levels. Research published in the Journal of Clinical Hypertension highlighted the superior efficacy of amlodipine in reducing systolic and diastolic blood pressure compared to other antihypertensive agents.
