Description
Cardipril (Ramipril) Capsules 2.5 mg. №30
Composition
The active ingredient in Cardipril is Ramipril. Each capsule contains 2.5 mg of Ramipril.
Mechanism of Action
Ramipril, the active ingredient in Cardipril, is an angiotensin-converting enzyme (ACE) inhibitor. It works by inhibiting ACE, an enzyme involved in the renin-angiotensin-aldosterone system, leading to vasodilation and reduced sodium retention, thereby lowering blood pressure and improving cardiac function.
Pharmacological Properties
Cardipril exerts its pharmacological effects by selectively inhibiting ACE, resulting in decreased levels of angiotensin II and aldosterone. This leads to vasodilation, reduced peripheral resistance, decreased blood volume, and lower blood pressure. Additionally, Cardipril helps in the prevention of cardiovascular events by its anti-hypertensive and cardioprotective actions.
Indications for Use
Cardipril is indicated for the treatment of hypertension to lower blood pressure and for the management of heart failure to improve cardiac function. It is also prescribed to reduce the risk of myocardial infarction, stroke, and death in patients at high cardiovascular risk.
Contraindications
- Cardipril is contraindicated in patients with a history of hypersensitivity to Ramipril or any other ACE inhibitor.
- It should not be used during pregnancy as it may cause harm to the fetus.
- Cardipril is not recommended for patients with severe renal impairment or end-stage renal disease.
- Patients with severe hepatic impairment should avoid Cardipril.
Side Effects
Common side effects of Cardipril may include dizziness, fatigue, cough, hypotension, and hyperkalemia. Rare but serious side effects may include angioedema, renal impairment, and neutropenia. It is important to report any adverse reactions to your healthcare provider.
Usage Instructions
Cardipril is typically initiated at a dose of 2.5 mg once daily. Your healthcare provider may adjust the dosage based on your individual response. The capsules can be taken with or without food. It is important to adhere to the prescribed dose and not alter the regimen without consulting your doctor.
Benefits Compared to Analogues
Cardipril offers several advantages over other ACE inhibitors due to its long duration of action, once-daily dosing convenience, and proven efficacy in reducing cardiovascular events. Additionally, Cardipril has a favorable side effect profile compared to some other medications in its class.
Suitable Patient Groups
Cardipril is suitable for adult patients with hypertension, heart failure, or those at high risk of cardiovascular events. It is not recommended for use in children, pregnant women, or individuals with severe renal or hepatic impairment without medical supervision. Elderly patients may require dosage adjustments based on their renal function.
Storage and Shelf Life
Store Cardipril capsules in a cool, dry place away from direct sunlight. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use the product beyond the specified shelf life.
Packaging Description
Cardipril capsules are typically packaged in blister packs containing 30 capsules each. The packaging is designed to protect the capsules from moisture and ensure their integrity until use. Each blister pack is labeled with the product name, dosage strength, and batch number for identification.
