Description

Cardosal (olmesartan medoxomi) Coated Tablets 20 mg. №28

Ingredients:

Each tablet contains 20 mg of olmesartan medoxomil as the active ingredient.

Dosage:

The recommended dosage is one tablet daily, or as directed by a healthcare professional.

Indications:

Cardosal tablets are indicated for the treatment of hypertension to lower blood pressure.

Contraindications:

Do not use Cardosal if you are pregnant, have severe renal impairment, or have a history of angioedema related to previous ACE inhibitor therapy.

Directions:

Swallow the tablet whole with water, with or without food.

Scientific Evidence:

Studies have shown that olmesartan medoxomil, the active ingredient in Cardosal, effectively reduces blood pressure by blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II. This action leads to vasodilation and decreased sodium reabsorption, resulting in lowered blood pressure levels.

Additional Information:

It is important to regularly monitor blood pressure levels while taking Cardosal to ensure optimal efficacy. In case of any adverse reactions or concerns, consult a healthcare provider immediately.

Pharmacological Effects:

Olmesartan medoxomil is a selective angiotensin II receptor antagonist that acts on the renin-angiotensin-aldosterone system. By blocking the binding of angiotensin II to its receptors, it inhibits the vasoconstrictor and aldosterone-secreting effects, leading to vasodilation and decreased sodium reabsorption. This mechanism helps in lowering blood pressure effectively.

Clinical Trials and Comparative Effectiveness:

In a comparative study published in the Journal of Hypertension, olmesartan medoxomil demonstrated superior efficacy in lowering blood pressure compared to other angiotensin receptor blockers. The study also highlighted the favorable safety profile of olmesartan medoxomil, making it a preferred choice in the management of hypertension.