Description
Carizon (clobetasol) Ointment 0.5 mg/1g, 30 g
Composition
The active ingredient in Carizon Ointment is clobetasol propionate, a potent corticosteroid. Each gram of the ointment contains 0.5 mg of clobetasol propionate.
Mechanism of Action
Clobetasol propionate exerts its pharmacological effects by binding to intracellular glucocorticoid receptors. This complex then binds to DNA elements, leading to the modulation of gene expression involved in inflammatory responses.
Pharmacological Properties
Carizon Ointment possesses potent anti-inflammatory, antipruritic, and vasoconstrictive properties attributed to clobetasol propionate, a high-potency corticosteroid.
Indications for Use
Carizon Ointment is indicated for the relief of inflammatory and pruritic manifestations associated with corticosteroid-responsive dermatoses. It is commonly used in conditions such as psoriasis and atopic dermatitis.
Contraindications
Carizon Ointment is contraindicated in individuals with a known history of hypersensitivity to clobetasol propionate, other corticosteroids, or any components of the ointment formulation. Avoid application on the face, underarms, or groin area unless under the guidance of a healthcare provider.
Side Effects
Common side effects of Carizon Ointment may include skin irritation, burning, itching, or dryness at the application site. Prolonged use or excessive dosage can lead to systemic side effects such as adrenal suppression or Cushing’s syndrome.
Usage Instructions
Apply a thin layer of Carizon Ointment to the affected skin areas once or twice daily, gently massaging it into the skin until fully absorbed. Avoid covering the treated area unless advised by a healthcare professional.
- Note: Carizon Ointment is for external use only. Avoid contact with the eyes.
- Warning: Prolonged use exceeding 2 weeks consecutively is generally discouraged without medical supervision.
Benefits Compared to Analogues
Carizon Ointment stands out from its analogues due to its high potency and efficacy in managing severe inflammatory skin conditions. The precise formulation of clobetasol propionate ensures rapid relief and symptom control in corticosteroid-responsive dermatoses.
Suitable Patient Groups
Carizon Ointment is suitable for adult patients and adolescents with dermatological conditions requiring potent corticosteroid therapy. Caution is advised when using in pediatric populations, and it should be avoided in infants unless deemed necessary by a healthcare provider.
Storage and Shelf Life
Store Carizon Ointment at room temperature away from moisture and heat. Ensure the cap is tightly closed after each use. Check the expiration date on the packaging and do not use the ointment beyond the specified shelf life.
Packaging Description
Carizon Ointment is available in tubes containing 30 grams of the ointment. The packaging is designed to maintain the stability and integrity of the product throughout its shelf life.
