Description
Cefazolin Powder for Solution for Injections 0.5 g. №10 Vial
Ingredients
The primary active ingredient in this product is Cefazolin. Each vial contains 0.5 g of Cefazolin.
Mechanism of Action
Cefazolin, a first-generation cephalosporin antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, leading to the disruption of the bacterial cell wall and eventual cell death.
Pharmacological Properties
Cefazolin demonstrates broad-spectrum activity against various Gram-positive and some Gram-negative bacteria. It exhibits excellent stability to beta-lactamases and is effective in treating infections caused by susceptible organisms.
Indications for Use
Cefazolin is indicated for the treatment of infections caused by susceptible bacteria, including skin and soft tissue infections, respiratory tract infections, urinary tract infections, and bone infections.
Contraindications
- Patients with a history of immediate hypersensitivity reactions to cephalosporins should avoid using Cefazolin.
- Avoid Cefazolin in individuals with a known history of severe renal impairment or gastrointestinal conditions such as colitis.
Side Effects
Common side effects of Cefazolin may include diarrhea, nausea, vomiting, rash, and injection site reactions. Serious but rare side effects may include severe allergic reactions and Clostridium difficile-associated diarrhea.
Usage Instructions
Cefazolin is typically administered via intramuscular or intravenous injection as prescribed by a healthcare professional. The dosage and frequency of administration are determined based on the type and severity of the infection. It is important to follow the healthcare provider’s instructions carefully.
Benefits Compared to Analogues
Cefazolin offers the advantage of a well-established safety profile and efficacy in treating a wide range of bacterial infections. Its first-generation cephalosporin structure provides reliable coverage against many pathogens, making it a preferred choice in certain clinical scenarios.
Suitable Patient Groups
Cefazolin can be used in various patient populations, including adults, children, and elderly individuals. Dosing adjustments may be necessary in patients with renal impairment to ensure appropriate drug levels and minimize the risk of adverse effects.
Storage and Shelf Life
Store Cefazolin powder for solution for injections as per the manufacturer’s instructions. Typically, it should be stored at controlled room temperature away from light and moisture. Check the product packaging for the expiry date and do not use expired medication.
Packaging Description
Cefazolin powder for solution for injections is supplied in vials containing 0.5 g of the active ingredient. Each package includes 10 vials for multiple doses. The packaging should be inspected for any signs of tampering before use.
