Description
Cefazolin Powder for Solution for Injections 0.5 g. N5
Composition
The main active ingredient in this pharmaceutical product is Cefazolin. Each vial contains 0.5 g of Cefazolin.
Mechanism of Action
Cefazolin is a first-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.
Pharmacological Properties
Cefazolin exhibits bactericidal activity against a wide range of gram-positive and some gram-negative bacteria. It is effective in treating infections caused by susceptible organisms.
Indications for Use
Cefazolin is indicated for the treatment of various infections caused by susceptible bacteria, including:
- Respiratory tract infections
- Urinary tract infections
- Skin and skin structure infections
- Biliary tract infections
- Bone and joint infections
Contraindications
Cefazolin is contraindicated in patients with a known allergy to cephalosporins. Additionally, individuals with a history of severe hypersensitivity reactions to other beta-lactam antibacterial drugs like penicillins or carbapenems should avoid using Cefazolin.
Side Effects
Common side effects of Cefazolin may include nausea, vomiting, diarrhea, and skin rash. Serious side effects such as allergic reactions and severe gastrointestinal disturbances are rare but possible.
Usage Instructions
Cefazolin is typically administered intravenously or intramuscularly. The recommended dosage for adults is 0.5 g to 1.0 g every 6 to 8 hours, adjusted based on the severity of the infection and the patient’s condition. It is crucial to follow the healthcare provider’s instructions for proper preparation and administration of the medication.
Benefits Compared to Analogues
Cefazolin offers broad-spectrum coverage against various bacterial pathogens, making it an effective choice for treating a wide range of infections. Its well-established safety profile and long history of clinical use contribute to its reliability and efficacy compared to newer cephalosporin antibiotics.
Suitable Patient Groups
Cefazolin can be used in both adult and pediatric populations for the treatment of bacterial infections. Dosing adjustments may be necessary in elderly patients or individuals with impaired renal function to prevent potential adverse effects.
Storage and Shelf Life
Cefazolin should be stored at room temperature away from moisture and light. The shelf life of the product is typically indicated on the packaging and should be checked before use to ensure potency and effectiveness.
Packaging Description
The product is available in vials containing 0.5 g of Cefazolin powder for reconstitution. Each package contains a specified number of vials, as indicated by the packaging label.
