Description
Cefoctam (Cefuroxime) Powder for Solution for Injections 0.75 g. №1 Vial
Composition
The main active ingredient in Cefoctam is Cefuroxime, a second-generation cephalosporin antibiotic.
Mechanism of Action
Cefoctam (Cefuroxime) exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, resulting in cell lysis and death.
Pharmacological Properties
Cefoctam (Cefuroxime) demonstrates broad-spectrum activity against various gram-positive and gram-negative bacteria. It shows stability against beta-lactamases, enhancing its efficacy against resistant strains.
Indications for Use
Cefoctam (Cefuroxime) is indicated for the treatment of infections caused by susceptible bacteria, including respiratory tract infections, skin and soft tissue infections, urinary tract infections, and septicemia.
Contraindications
- Allergy: Cefoctam is contraindicated in patients with a known hypersensitivity to Cefuroxime or other cephalosporins.
- Kidney Disease: Patients with severe renal impairment should adjust the dosage under medical supervision.
Side Effects
Common side effects of Cefoctam may include gastrointestinal disturbances, hypersensitivity reactions, and superinfections. Severe adverse effects like anaphylaxis and pseudomembranous colitis are rare but possible.
Usage Instructions
Cefoctam (Cefuroxime) is administered via intramuscular or intravenous injection as prescribed by a healthcare provider. Dosage is individualized based on the infection type and severity. Proper training is essential for safe administration.
Benefits Compared to Analogues
Cefoctam offers enhanced stability against beta-lactamases, expanding its spectrum of activity and efficacy against resistant bacteria compared to some first-generation cephalosporins.
Suitable Patient Groups
Cefoctam can be used in pediatric and adult populations, including elderly patients. Dosage adjustments may be necessary in individuals with renal impairment.
Storage and Shelf Life
Cefoctam should be stored at controlled room temperature away from moisture and light. The shelf life of the product is typically mentioned on the packaging and should be adhered to for optimal efficacy.
Packaging Description
Cefoctam is available in single-dose vials containing 0.75 g of Cefuroxime powder for reconstitution. Each vial is labeled with the necessary instructions for proper preparation and administration.
