Description
Ceftriaxon (Ceftriaxone) Powder for Solution for Injections 1g. N5 Vial
Composition
The main active ingredient in this product is Ceftriaxone. Each vial contains 1g of Ceftriaxone.
Mechanism of Action
Ceftriaxone, a third-generation cephalosporin antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, leading to cell death.
Pharmacological Properties
Ceftriaxone demonstrates broad-spectrum activity against various Gram-positive and Gram-negative bacteria. It exhibits high stability against beta-lactamases, enhancing its efficacy against resistant strains.
Indications for Use
Ceftriaxone is indicated for the treatment of infections caused by susceptible bacteria, including respiratory tract infections, skin and soft tissue infections, urinary tract infections, septicemia, and meningitis.
Contraindications
- Allergy: Ceftriaxone is contraindicated in individuals with a history of hypersensitivity to Ceftriaxone or other cephalosporin antibiotics.
- Severe Renal Impairment: Use of Ceftriaxone is cautioned in patients with severe renal impairment due to the risk of accumulation and potential toxicity.
Side Effects
Common side effects of Ceftriaxone may include diarrhea, nausea, vomiting, rash, and injection site reactions. Serious adverse effects such as allergic reactions and Clostridium difficile-associated diarrhea may occur rarely.
Usage Instructions
Ceftriaxone is administered via intramuscular or intravenous route as prescribed by the healthcare provider, typically given once or twice daily. Dosage and duration of therapy should be individualized based on the infection type and severity.
Benefits Compared to Analogues
Ceftriaxone offers the advantage of broad antibacterial coverage, including activity against beta-lactamase-producing strains, making it a valuable choice for empiric therapy in various infections.
Suitable Patient Groups
Ceftriaxone can be used in pediatric and adult populations, with dosage adjustments made for age and renal function. Caution is advised in elderly patients and those with hepatic impairment.
Storage and Shelf Life
Store Ceftriaxone according to the manufacturer’s instructions, typically at room temperature away from light and moisture. Check the product packaging for the expiration date and do not use expired medication.
Packaging Description
Each package of Ceftriaxone Powder for Solution for Injections contains 5 vials, each vial containing 1g of Ceftriaxone. The packaging is designed to maintain product integrity and sterility.
