Description

Clopidogrel Coated Tablets 0.075 g. №10

Ingredients

Composition: Each tablet contains 0.075 g of Clopidogrel as the active ingredient. Inactive ingredients may include lactose, microcrystalline cellulose, hydroxypropyl cellulose, and magnesium stearate.

Mechanism of Action

Pharmacological Properties: Clopidogrel works by irreversibly binding to the P2Y12 receptor on platelets, inhibiting platelet aggregation and reducing the formation of blood clots. This mechanism helps prevent thrombotic events in patients at risk of cardiovascular complications.

Indications for Use

Indications: Clopidogrel tablets are indicated for the prevention of blood clots in patients with a history of heart attack, stroke, or peripheral artery disease. It is also used in combination with aspirin for certain heart conditions.

Contraindications

Contraindications: Do not use Clopidogrel if you have an allergy to the drug or any of its components. Patients with active bleeding conditions or recent surgery should also avoid this medication.

Side Effects

Side Effects: Common side effects may include bruising, bleeding, and gastrointestinal disturbances. Serious side effects such as severe bleeding or allergic reactions are rare but require immediate medical attention.

Usage Instructions

Usage: The usual dose is one tablet daily, taken orally with or without food. Dosage may vary based on individual medical conditions, so consult a healthcare provider for personalized recommendations.

Benefits Compared to Analogues

Benefits: Clopidogrel has been shown to be as effective as or even superior to other antiplatelet agents in preventing cardiovascular events. Studies have demonstrated its efficacy in reducing the risk of recurrent heart attacks and strokes in high-risk patients.

Suitable Patient Groups

Patient Groups: Clopidogrel can be used in various patient populations, including adults, elderly individuals, and certain pediatric cases under medical supervision. Dosage adjustments may be necessary based on age and health status.

Storage and Shelf Life

Storage: Store Clopidogrel tablets in a cool, dry place away from moisture and sunlight. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use expired tablets.

Packaging Description

Packaging: Each pack contains 10 coated tablets of Clopidogrel 0.075 g. The packaging is designed to protect the tablets from environmental factors and ensure product integrity.

Scientific Evidence

Scientific Evidence: Clopidogrel is supported by extensive research demonstrating its efficacy in reducing the risk of cardiovascular events. Studies published in reputable journals like the New England Journal of Medicine have highlighted its role in preventing recurrent heart attacks and strokes in high-risk patients.

Additional Information

Important Note: Inform your healthcare provider about all medications, supplements, and medical conditions before starting Clopidogrel therapy. Regular monitoring of blood parameters may be necessary during treatment to ensure safety and efficacy.

Clinical Trials: Clinical trials have shown that Clopidogrel is effective in preventing cardiovascular events. A study published in Circulation compared Clopidogrel with aspirin in reducing the risk of recurrent strokes, with Clopidogrel demonstrating favorable outcomes in certain patient populations.