Description

Clopidogrel Coated Tablets 0.075 g. №10

Ingredients

Each tablet contains 0.075 g of Clopidogrel as the active ingredient. Inactive ingredients may include lactose, microcrystalline cellulose, hydroxypropyl cellulose, and magnesium stearate.

Dosage

The usual dose is one tablet daily, taken orally with or without food. Dosage may vary based on individual medical conditions, so consult a healthcare provider for personalized recommendations.

Indications

Clopidogrel tablets are indicated for the prevention of blood clots in patients with a history of heart attack, stroke, or peripheral artery disease. It is also used in combination with aspirin for certain heart conditions.

Contraindications

Do not use Clopidogrel if you have an allergy to the drug or any of its components. Patients with active bleeding conditions or recent surgery should also avoid this medication.

Directions

Follow the instructions provided by your healthcare provider or pharmacist. Do not change the dosage or stop taking the medication without consulting a medical professional.

Scientific Evidence

Clopidogrel is a widely studied antiplatelet medication that has shown significant efficacy in reducing the risk of cardiovascular events. Research published in the New England Journal of Medicine has demonstrated the benefits of Clopidogrel in preventing recurrent heart attacks and strokes in high-risk patients.

Additional Information

It is essential to inform your healthcare provider about all medications, supplements, and medical conditions before starting Clopidogrel therapy. Regular monitoring of blood parameters may be necessary during treatment to ensure safety and efficacy.

Pharmacological Effects: Clopidogrel works by irreversibly binding to the P2Y12 receptor on platelets, inhibiting platelet aggregation and reducing the formation of blood clots. This mechanism helps prevent thrombotic events in patients at risk of cardiovascular complications.

Clinical Trials: Clinical trials have shown that Clopidogrel is as effective as or even superior to other antiplatelet agents in preventing cardiovascular events. A study published in Circulation compared the efficacy of Clopidogrel with aspirin in reducing the risk of recurrent strokes, with Clopidogrel demonstrating better outcomes in certain patient populations.