Description
Denigma (Memantine) Coated Tablets 10 mg. №140
Composition
Active ingredient: Memantine hydrochloride. Other ingredients include microcrystalline cellulose, colloidal silicon dioxide, talc, and magnesium stearate.
Mechanism of Action
Pharmacological Properties: Memantine works by regulating the activity of glutamate, a neurotransmitter involved in learning and memory. By blocking excessive glutamate activity, memantine helps protect brain cells from damage in Alzheimer’s disease.
Indications for Use
Denigma (Memantine) Coated Tablets are indicated for the treatment of moderate to severe Alzheimer’s disease.
Contraindications
Do not use Denigma (Memantine) Coated Tablets if:
- You are allergic to memantine or any other ingredients in the product.
- You have severe kidney problems.
- You are pregnant or breastfeeding.
Side Effects
Common side effects may include dizziness, headache, constipation, and confusion. Contact your healthcare provider if you experience any severe side effects.
Usage Instructions
Recommended Dosage: The usual starting dose is 5 mg once daily. The dose is then increased by 5 mg at weekly intervals. The maximum recommended dose is 20 mg per day. Take Denigma (Memantine) Coated Tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with water. Do not crush or chew the tablet.
Benefits Compared to Analogues
Denigma (Memantine) Coated Tablets offer improved cognitive function and slower disease progression compared to traditional Alzheimer’s treatments. The controlled dosage escalation reduces the risk of adverse effects.
Suitable Patient Groups
Denigma (Memantine) Coated Tablets are suitable for adult patients with moderate to severe Alzheimer’s disease. Dosage adjustments may be necessary for elderly patients and those with renal impairment. Consult your healthcare provider for personalized recommendations.
Storage and Shelf Life
Store Denigma (Memantine) Coated Tablets in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description
Each package contains 140 coated tablets of Denigma (Memantine) 10 mg. The tablets are sealed in a blister pack to maintain their integrity and potency.
Clinical Evidence and Proven Effectiveness
Scientific studies have shown that memantine, the active ingredient in Denigma tablets, can help improve cognitive function and slow down the progression of Alzheimer’s disease. Research published in the Journal of Alzheimer’s Disease demonstrated the efficacy of memantine in improving memory and daily functioning in patients with Alzheimer’s.
Clinical Trials: Clinical trials have shown that memantine is well-tolerated and effective in improving cognitive function and behavior in patients with Alzheimer’s disease. A study published in the New England Journal of Medicine reported that memantine treatment resulted in significant improvements in cognitive and functional abilities compared to a placebo.
