Description

Diclak ID (diclofenac) tablets 75 mg. №100

Ingredients

Active ingredient: Each tablet contains 75 mg of diclofenac sodium.

Dosage

Recommended dosage: The usual dose is 75-150 mg daily in divided doses.

Indications

Indicated for: Relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Contraindications

Do not use if: Allergic to diclofenac, have a history of gastrointestinal bleeding, or in the third trimester of pregnancy.

Directions

Administration: Swallow the tablets whole with a full glass of water. Do not crush or chew.

Scientific Evidence

Diclak ID (diclofenac) tablets 75 mg have been extensively studied for their efficacy in managing pain and inflammation. Research published in the Journal of Pain Research has shown that diclofenac is effective in reducing pain intensity and improving physical function in patients with osteoarthritis.

Additional Information

It is important to note that diclofenac may increase the risk of cardiovascular events, especially when used at high doses or for long durations. Patients with a history of heart disease should use this medication with caution and under medical supervision.

Pharmacological Effects

Diclak ID (diclofenac) tablets belong to the class of nonsteroidal anti-inflammatory drugs (NSAIDs) and work by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the production of prostaglandins that cause pain and inflammation. This action helps alleviate symptoms associated with various inflammatory conditions.

Clinical Trials and Comparative Effectiveness

In a comparative study published in the Journal of Clinical Rheumatology, diclofenac was found to be as effective as other NSAIDs in relieving pain and improving joint function in patients with rheumatoid arthritis. The study also highlighted the favorable safety profile of diclofenac compared to other NSAIDs.