Description

Diclak ID (diclofenac) tablets with modified release 150 mg. №100

Ingredients

Active ingredient: Each tablet contains 150 mg of diclofenac with modified release.

Dosage

Recommended dosage: The usual dose is 1 tablet once daily, preferably with food.

Indications

Indicated for: Relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

Contraindications

Do not use if: Allergic to diclofenac, have a history of gastrointestinal bleeding, or during the third trimester of pregnancy.

Directions

Administration: Swallow the tablet whole with a glass of water. Do not crush or chew.

Scientific Evidence

Diclak ID tablets with modified release have been studied extensively for their efficacy in managing pain and inflammation. Clinical trials have shown that diclofenac, the active ingredient, effectively reduces pain intensity and improves joint function in patients with various inflammatory conditions.

Additional Information

It is important to note that diclofenac, like other nonsteroidal anti-inflammatory drugs (NSAIDs), may increase the risk of cardiovascular events and gastrointestinal complications. Patients should be monitored closely for such adverse effects during treatment.

Pharmacological Effects

Diclak ID tablets work by inhibiting the enzyme cyclooxygenase (COX), thereby reducing the production of prostaglandins that cause pain and inflammation. The modified release formulation ensures a sustained effect, providing long-lasting relief for patients.

Clinical Trials and Comparative Effectiveness

In a comparative study published in the Journal of Pain Research, diclofenac with modified release demonstrated similar efficacy to other NSAIDs in managing chronic pain conditions. The controlled-release formulation offered the advantage of less frequent dosing and improved patient compliance.