Description

Dicloberl (diclofenac sodium) retard capsules with prolonged release 100 mg. №20

Ingredients

Active ingredient: Each capsule contains 100 mg of diclofenac sodium. Other ingredients include lactose monohydrate, maize starch, povidone, and magnesium stearate.

Dosage

Recommended dosage: The usual dose is one capsule daily, preferably taken with food. Do not exceed the recommended dose unless directed by a healthcare provider.

Indications

Indicated for: Relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout.

Contraindications

Do not use if: Allergic to diclofenac or other NSAIDs, have a history of gastrointestinal bleeding, or in the third trimester of pregnancy.

Directions

Directions for use: Swallow the capsule whole with a glass of water. Do not crush or chew the capsule. Follow the instructions provided by your healthcare provider.

Scientific Evidence

Pharmacological effects: Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, thereby reducing pain and inflammation. The prolonged-release formulation ensures a steady concentration of the drug in the bloodstream, providing long-lasting relief.

Clinical trials: Clinical studies have demonstrated the efficacy of diclofenac sodium in managing various painful conditions. A study published in the Journal of Pain Research showed that diclofenac provided significant pain relief in patients with osteoarthritis compared to placebo.

Additional Information

Warnings: Long-term use of NSAIDs like diclofenac may increase the risk of cardiovascular events and gastrointestinal complications. It is important to use the lowest effective dose for the shortest duration possible.

Storage: Store the capsules at room temperature away from moisture and heat. Keep out of reach of children.