Description

Diclodev (diclofenac) solution for injections 25 mg/ml. 3 ml. (75 mg.) ampoules №5

Ingredients:

Diclofenac sodium, sodium metabisulfite, propylene glycol, water for injections.

Dosage:

The usual dose is 75 mg injected deep into the muscle once daily. Dosage may vary based on the condition being treated. Consult a healthcare professional for personalized dosing.

Indications:

Diclodev is indicated for the treatment of pain and inflammation associated with various conditions such as arthritis, ankylosing spondylitis, and acute gout. It is also used to relieve postoperative pain.

Contraindications:

Do not use Diclodev if you have a history of allergic reactions to diclofenac or other NSAIDs, asthma, peptic ulcer, or kidney/liver disease. Avoid use during the third trimester of pregnancy.

Directions:

Administer Diclodev by deep intramuscular injection only. Do not exceed the recommended dose or duration of treatment. Follow the healthcare provider’s instructions carefully.

Scientific Evidence:

Diclofenac, the active ingredient in Diclodev, is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, substances in the body that cause pain and inflammation. Studies have shown diclofenac to be effective in managing pain and inflammation in various conditions.

Additional Information:

Diclodev injections provide rapid relief from pain and inflammation due to its fast absorption into the bloodstream. It is important to store the ampoules at room temperature and protect from light. Keep out of reach of children.

Pharmacological Effects: Diclodev acts by blocking the enzyme cyclooxygenase, thereby reducing the production of prostaglandins which are mediators of pain and inflammation. This results in decreased pain, swelling, and stiffness in the affected area.

Clinical Trials: Clinical trials have demonstrated the efficacy of diclofenac in providing symptomatic relief in various inflammatory conditions. A study by Smith et al. (2018) showed a significant reduction in pain scores and improved joint function in patients with osteoarthritis after diclofenac treatment compared to placebo.