Description

Diclofenak (Diclofenac) Ampoules 2.5% 3 ml. №5

Ingredients:

Diclofenac sodium, water for injections, sodium metabisulfite.

Dosage:

The usual dose is 75-150 mg per day in divided doses. Dosage may vary based on the condition being treated. Always consult a healthcare professional for appropriate dosing.

Indications:

Diclofenak ampoules are indicated for the relief of pain and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gout.

Contraindications:

Do not use Diclofenak ampoules if you have a history of allergic reactions to diclofenac or other NSAIDs, active peptic ulcer, severe heart failure, or during the third trimester of pregnancy.

Directions:

Administer the contents of the ampoule via intramuscular or intravenous injection as directed by a healthcare provider. Do not exceed the recommended dose.

Scientific Evidence:

Diclofenac, the active ingredient in Diclofenak ampoules, has been extensively studied for its efficacy in managing pain and inflammation. Research published in the journal Pain Research and Treatment demonstrated the superior analgesic effect of diclofenac compared to placebo in patients with osteoarthritis. Additionally, a meta-analysis published in the Cochrane Database of Systematic Reviews found diclofenac to be as effective as other NSAIDs in treating various inflammatory conditions.

Additional Information:

It is important to monitor for potential side effects such as gastrointestinal bleeding, renal impairment, and cardiovascular risks when using diclofenac. Patients with a history of these conditions should use this medication with caution. Always follow the guidance of a healthcare professional when using Diclofenak ampoules.

Pharmacological Effects: Diclofenac works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins which are mediators of pain and inflammation in the body. This action helps alleviate symptoms associated with various inflammatory conditions.

Clinical Trials: Clinical trials have shown that diclofenac provides rapid and effective relief of pain and inflammation in conditions such as rheumatoid arthritis and osteoarthritis. A study published in the Journal of Clinical Rheumatology reported significant improvements in pain scores and joint function in patients treated with diclofenac compared to placebo.