Description

Diclofenak (Diclofenac) Gel 1% 40 g. Tube

Ingredients

Active ingredient: Diclofenac Sodium 1%
Other ingredients: Carbomer, cocoyl caprylocaprate, diethylamine, isopropyl alcohol, liquid paraffin, macrogol cetostearyl ether, perfume cream 45, propylene glycol, and purified water.

Dosage

Apply a thin layer of Diclofenak gel to the affected area 3-4 times a day. Rub gently into the skin. Do not cover with a bandage unless directed by a healthcare provider.

Indications

Diclofenak gel is indicated for the relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It helps reduce swelling and joint pain, improving mobility.

Contraindications

Do not use Diclofenak gel if you are allergic to diclofenac or any other ingredients in the gel. Avoid applying to broken or irritated skin, eyes, or mucous membranes.

Directions

Wash hands before and after applying the gel. Squeeze a small amount onto the affected area and gently massage. Avoid contact with eyes and mucous membranes. Do not ingest.

Scientific Evidence

Diclofenac, the active ingredient in Diclofenak gel, has been extensively studied for its efficacy in managing pain and inflammation. Research published in the Journal of Clinical Pharmacology demonstrated the superior anti-inflammatory effects of diclofenac compared to placebo in patients with osteoarthritis.

Additional Information

Diclofenak gel offers localized relief with minimal systemic absorption, reducing the risk of systemic side effects associated with oral NSAIDs. It provides a convenient and targeted approach to pain management, making it a preferred choice for many patients.

Pharmacological Effects: Diclofenac works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins involved in inflammation and pain. This action helps alleviate symptoms and improve function in various inflammatory conditions.

Clinical Trials: Clinical trials have shown that diclofenac gel is as effective as oral diclofenac in providing pain relief with fewer systemic side effects. A study published in the Journal of Rheumatology found that diclofenac gel provided rapid and sustained pain relief in patients with knee osteoarthritis.